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Empowering Science in SA with Pre-Loved Analytical Instruments

In the pursuit of scientific advancement, access to high-quality laboratory equipment is essential. However, for many educational institutions and small research organisations, acquiring the necessary analytical instruments remains a challenge due to budget constraints. Recognising this need, Agilent Technologies has partnered with Seeding Labs, a non-profit organisation dedicated to equipping scientists in resource-limited areas with the tools they need to drive innovation. In South Africa, Chemetrix is proud to be part of this initiative, facilitating the handover of previously used Agilent instruments to deserving universities, technical colleges, and research institutions.

Seeding Labs: A catalyst for scientific growth

Seeding Labs is an award-winning nonprofit that has spent the last 15 years working to overcome a major barrier to global development: the extreme concentration of scientific capacity in just a handful of countries. Since 2008, Seeding Labs has provided scientific institutions in developing countries with access to modern lab equipment and supplies through our flagship program, Instrumental Access.

This initiative has been instrumental in bridging the global equipment gap by collecting and redistributing used but fully functional laboratory instruments to institutions that need them most. It ensures that scientists can continue their research and contribute to scientific progress regardless of financial limitations.

Agilent’s participation in this initiative underscores its commitment to corporate social responsibility and sustainable scientific development. By donating previously used instruments, Agilent not only supports education and research but also promotes a more sustainable approach to laboratory operations by extending the lifecycle of high-quality equipment.

Chemetrix: Facilitating impactful change in South Africa

As a leading distributor of Agilent technologies in Southern Africa, Chemetrix has been entrusted with coordinating the transfer of these essential instruments to local educational and research institutions. With a deep understanding of the needs of the scientific community, Chemetrix is uniquely positioned to ensure that the right equipment reaches the right organisations, where it can have the greatest impact.

Through this initiative, Chemetrix is helping to:

Enhance STEM education: By providing universities and technical colleges with advanced analytical instruments, students gain hands-on experience with industry-standard equipment, better preparing them for careers in science and technology.
Strengthen research capabilities: Many research institutions struggle with outdated or insufficient equipment. By receiving Agilent instruments, these institutions can conduct higher-quality research, fostering innovation and scientific breakthroughs.
Support small enterprises and startups: In addition to academic institutions, small businesses focused on analytical services and product development can benefit from access to these instruments, driving economic growth and technological advancement.

Bringing world-class technology to local institutions

The Agilent instruments being donated are meticulously refurbished and tested to ensure their reliability and performance. These include essential laboratory tools such as gas chromatographs (GC), liquid chromatographs (LC), and spectrophotometers, which are widely used in chemical analysis, environmental testing, pharmaceutical development, and food safety testing.

For a university chemistry lab, an Agilent GC system could mean the difference between theoretical learning and practical application. For a research institute working on climate change, an LC system could be the key to analysing environmental pollutants with precision. For a startup developing new pharmaceuticals, these instruments could accelerate drug discovery and testing, providing the foundation for innovation.

A sustainable and inclusive approach to scientific advancement

This collaboration between Agilent, Seeding Labs, and Chemetrix is more than just an instrument donation programme; it represents a long-term investment in scientific capability and education. By repurposing high-quality analytical instruments, the programme not only empowers the next generation of scientists but also supports sustainability by reducing electronic waste and extending the usability of valuable equipment.

Chemetrix’s involvement ensures that the process is efficient, transparent, and tailored to the specific needs of local institutions. With its strong network and expertise, Chemetrix is playing a vital role in ensuring that the donated equipment is deployed effectively, maximising its impact across various scientific disciplines.

📚 Download the Sustainable Alternatives for Acquiring the Latest Technologies infographic and discover how Agilent can help you reach your sustainability goals by keeping useful equipment out of landfills, while maximising your lab productivity. >

Looking ahead: The future of science in South Africa

The demand for skilled scientists and researchers continues to grow, and initiatives like this play a crucial role in developing a well-equipped workforce. By facilitating the donation of Agilent’s previously used instruments, Chemetrix is helping South African institutions build state-of-the-art laboratories, enhance research capabilities, and produce graduates who are ready to contribute to the global scientific community.

As this initiative expands, Chemetrix remains committed to fostering a culture of collaboration, sustainability, and scientific excellence. By supporting education and research, Agilent, Seeding Labs, and Chemetrix are ensuring that innovation is not limited by geography or resources, but instead driven by curiosity, dedication, and access to the right tools.

For more information on how your institution can benefit from this initiative, contact us today.

Boost Your Lab’s Performance with Chemetrix’s Latest Agilent Additions

Every lab wants to know that it’s got tools that are reliable and that have the technology to help achieve it’s goals. Perhaps it’s time to replace the trusted instruments that have been in use for years because more space or efficiency is needed. Perhaps the lab is expanding and needs new instruments to accommodate the additional workload. Whatever your lab’s need may be, we’ve got you covered.

Chemetrix is thrilled to announce the expansion of our portfolio with the latest state-of-the-art instruments from Agilent Technologies. These cutting-edge additions are set to revolutionise laboratory workflows, offering unparalleled performance, efficiency, and reliability.

Agilent 8850 GC system: Compact yet powerful

The Agilent 8850 Gas Chromatograph (GC) System is a game-changer for laboratories seeking high performance in a compact design. Tailored for single-channel applications, the 8850 GC is ideal for routine analyses in environmental, food, and pharmaceutical sectors.

Key Features:

Compact design: Occupying minimal bench space, the 8850 GC is perfect for laboratories with space constraints.
Rapid heating: Equipped with a direct heating oven, it ensures swift temperature ramping, significantly reducing analysis time.
User-friendly interface: The intuitive touchscreen interface simplifies operation, making it accessible even for users with minimal GC experience.
Energy efficiency: Designed with energy conservation in mind, the 8850 GC consumes less power, contributing to sustainable laboratory practices.

By integrating the 8850 GC into your laboratory, you can expect enhanced throughput, reduced operational costs, and reliable results, making it an invaluable asset for routine GC analyses.

From monitoring air and water quality to detecting contaminants in soil, environmental laboratories require highly sensitive instrumentation. The 8850 GC is an excellent solution for testing volatile organic compounds (VOCs) and pollutants in environmental samples. It also offers fast and reliable results for characterising crude oil, gas composition, and refining processes for the petrochemical industry and precise analysis of hydrocarbons, fuels, and lubricants.

🖥️ Watch the GC Method Development from Beginner to Expert webinar to discuss what to consider, where to start, and what to optimise – focusing on inlet parameters, column selection, and oven programming. >

Agilent Infinity III LC series: A new era of liquid chromatography

Agilent’s Infinity III LC Series is engineered to meet the demands of modern laboratories, providing increased precision, reliability, and flexibility. With new features that enhance workflow efficiency, the Infinity III LC Series sets a new standard for high-performance liquid chromatography (HPLC) and ultra-high-performance liquid chromatography (UHPLC).

Key Features:

Optimised system performance: The Infinity III LC Series offers improved pressure resilience, higher flow rates, and enhanced detector sensitivity, making it ideal for both routine and complex analytical tasks.
InfinityLab technology: Integrated with InfinityLab Assist, this system provides real-time monitoring and diagnostics, reducing downtime and improving instrument longevity.
Versatile applications: Designed for seamless integration into regulated environments, it supports pharmaceuticals, food safety, environmental testing, and more.

By incorporating the Infinity III LC Series, laboratories can expect heightened accuracy, faster analysis times, and superior reproducibility—key factors for high-throughput environments.

📚 Download the HPLC Made For Tomorrow brochure and discover how the Agilent InfinityLab LC Solutions provide the broadest range of liquid chromatography options for any application and budget.

Precision and reliability are essential in pharmaceutical and biopharmaceutical analysis, where strict regulatory compliance is required. Infinity III is designed for high-throughput drug development, stability testing, and impurity profiling. It offers a cost-effective solution for routine quality control and formulation analysis, making it a trusted choice for pharmaceutical manufacturing. It is also particularly effective in pesticide residue analysis, mycotoxin screening, and nutritional profiling for the food and beverage sector.

Transform your laboratory with Agilent and Chemetrix

At Chemetrix, we are committed to providing cutting-edge solutions that empower laboratories to excel. The introduction of the Agilent Infinity III LC Series and 8850 GC System to our portfolio ensures that our clients have access to the latest advancements in analytical instrumentation.

From pharmaceutical quality control and food safety analysis to petrochemical testing and life sciences research, these powerful instruments enhance productivity, accuracy, and efficiency.

Discover how Agilent’s latest innovations can redefine your lab’s potential – contact Chemetrix today for expert guidance and support.

Ensuring Food Safety with Mass Spectrometry

In an interconnected world where food production and trade span continents, ensuring the safety and quality of food products has become a critical priority. Rising consumer expectations and increasingly stringent regulatory standards mean stakeholders in the food industry must navigate a complex web of challenges. From detecting contaminants to meeting compliance requirements, the stakes are high. This is where cutting-edge technologies like mass spectrometry are stepping in to revolutionise food safety testing, delivering unmatched precision, efficiency, and reliability.

The growing importance of Food Safety

Food safety is non-negotiable. Defined by the World Health Organization (WHO) as the prevention of hazards – both chronic and acute – that can harm consumer health, it forms the backbone of a trustworthy food supply chain. Hazards may include microbial contamination, pesticide residues, heavy metals, and even naturally occurring toxins, all of which can pose serious risks if left unchecked.

Food quality, while often considered alongside safety, addresses different concerns. It encompasses attributes such as flavour, texture, appearance, and even the origin of a product. While safety ensures a product is fit for consumption, quality determines its value and appeal to consumers.

For food producers, striking a balance between these two aspects is essential to building trust and maintaining competitiveness.

Why Mass Spectrometry?

Mass spectrometry has become a cornerstone of modern food safety testing, thanks to its unparalleled sensitivity, accuracy, and versatility. Unlike traditional methods, which may require separate tests for different contaminants, mass spectrometry can detect and quantify multiple analytes in a single run. This capability significantly enhances efficiency and reduces the time required for analysis – a critical advantage for laboratories handling high sample volumes.

Key Advantages of Mass Spectrometry in Food Safety

Unmatched sensitivity and precision

Mass spectrometry can detect contaminants at trace levels, often in parts per billion (ppb) or even parts per trillion (ppt). This is vital as regulatory agencies worldwide demand more stringent detection limits to protect public health.

Multi-analyte detection

With mass spectrometry, laboratories can analyse multiple contaminants simultaneously, including pesticides, heavy metals, mycotoxins, and allergens. This not only improves throughput but also reduces the cost and complexity of testing.

Simplified sample preparation

Advanced mass spectrometry systems streamline sample preparation, reducing the likelihood of human error while speeding up the testing process.

Adaptability across food matrices

From solid foods like grains and meats to liquids like milk and juices, mass spectrometry can handle diverse food matrices, making it a versatile solution for the food industry.

📚 Download the Food Safety Applications in Mass Spectrometry primer for a practical reference for applying current developments in Agilent MS technologies to food analysis: https://chemetrix.co.za/wp-content/uploads/2024/12/5989-1270EN-AGI_74_combined.pdf

Transforming Food Safety Testing

One of the most significant developments in mass spectrometry is the rise of inductively coupled plasma mass spectrometry (ICP-MS). Historically viewed as complex and challenging to operate, ICP-MS has undergone a transformation. Modern instruments now feature user-friendly interfaces, automated optimisation, and built-in diagnostic tools, making them accessible to labs of all sizes.

ICP-MS is particularly valuable for detecting heavy metals such as lead, cadmium, and mercury, which can have severe health consequences even at low concentrations. The technique’s sensitivity and specificity ensure that contaminants are accurately identified and quantified, enabling producers to meet regulatory requirements with confidence.

Another breakthrough is the integration of liquid chromatography-mass spectrometry (LC-MS) and gas chromatography-mass spectrometry (GC-MS). These methods are widely used for detecting pesticide residues and volatile organic compounds in food products. The combination of chromatography and mass spectrometry allows for the separation and precise identification of compounds within complex mixtures, ensuring reliable results.

📚 Download the Improving Food Safety Analysis with LC/Q-TOF compendium of application notes and explore analysis of pesticides, nontargeted screening approaches for contaminants, and food authenticity testing: https://chemetrix.co.za/wp-content/uploads/2024/12/Improving_Food_Safety_Analysis-with-LC_Q-TOF-Feb2020.pdf

Addressing the challenges of a globalised food supply chain

In a globalised food economy, the complexity of supply chains adds another layer of risk. Ingredients sourced from diverse regions can introduce contaminants at various stages, making robust testing protocols indispensable. Additionally, the transportation and storage of food products can create opportunities for microbial growth or chemical alterations.

Regulatory bodies worldwide, such as the European Food Safety Authority (EFSA) and the United States Food and Drug Administration (FDA), have responded by tightening standards and lowering acceptable thresholds for contaminants. As a result, food manufacturers must adopt advanced technologies to stay ahead of compliance requirements.

Mass spectrometry provides the tools needed to address these challenges. Offering rapid, reliable testing, enables stakeholders to identify potential issues early in the supply chain. For example, a shipment of imported spices can be tested for pesticide residues before distribution, preventing contaminated products from reaching consumers.

Moreover, mass spectrometry supports traceability – a key component of modern food safety systems. By linking test results to specific batches or production lots, producers can quickly identify and recall affected products in the event of a safety breach. This level of accountability is essential for maintaining consumer trust and avoiding costly disruptions.

📚 Download the Multi-Residue Pesticide Analysis in Food Matrices poster to see how the screening and quantitation of 250 pesticides was done using the Agilent Ultivo Triple Quad: https://chemetrix.co.za/wp-content/uploads/2024/12/Multi-Residue_Pesticide_Analysis-_Food_Matrices_Ultivo_AOAC_2017_PW044.pdf

Chemetrix: Your partner in Food Safety

Chemetrix is at the forefront of delivering advanced mass spectrometry solutions tailored to the needs of the food industry. With a deep understanding of the unique challenges faced by producers, regulatory agencies, and testing laboratories, Chemetrix provides comprehensive support to ensure optimal performance and compliance.

Why choose Chemetrix?

Cutting-Edge Instrumentation: Chemetrix offers state-of-the-art mass spectrometry systems, including ICP-MS, LC-MS, and GC-MS, designed for precision and efficiency.
Expert Guidance: From installation to training and ongoing support, Chemetrix’s team of experts ensures that clients can fully leverage their technology investments.
Tailored Solutions: Recognising that every client has unique requirements, Chemetrix works closely with stakeholders to develop customised workflows that meet their specific needs.

By partnering with Chemetrix, food producers and testing labs gain access to the tools and expertise needed to navigate the complexities of modern food safety testing with confidence.

The Future of Food Safety

As food systems evolve, so too must the methods used to ensure their safety. Mass spectrometry represents a critical step forward, offering the precision, speed, and adaptability needed to meet the challenges of an increasingly interconnected world.

For the food industry, adopting advanced testing technologies is not just about compliance – it’s about safeguarding public health, protecting brand reputation, and building trust with consumers. With partners like Chemetrix leading the way, the future of food safety is brighter, more secure, and more innovative than ever.

Emerging Trends in Environmental Testing

In recent years, environmental testing has undergone a remarkable transformation as the world faces mounting challenges related to pollution, climate change, and public health. Laboratories are tasked with identifying a growing list of contaminants, many of which were previously undetected or unregulated. Among these, per- and poly-fluoroalkyl substances (PFAS), often referred to as “forever chemicals,” have emerged as a significant concern due to their persistence in the environment and potential health impacts.

There are important key trends shaping the future of environmental testing. We will share some of the technologies and techniques that enable labs to meet evolving demands.

The growing importance of Environmental Testing

Environmental testing plays a crucial role in monitoring and safeguarding the health of ecosystems and communities. As scientific understanding of contaminants deepens, regulatory frameworks worldwide are becoming more stringent. Laboratories must now detect pollutants at trace levels, often within highly complex matrices like soil, water, and air.

Key drivers for innovation in environmental testing include:

Emerging Contaminants: Substances like PFAS, pharmaceuticals, and microplastics are increasingly being scrutinised due to their widespread presence and potential risks.
Tighter Regulations: Agencies such as the European Chemicals Agency (ECHA) and the United States Environmental Protection Agency (EPA) are implementing stricter standards for environmental monitoring.
Technological Advancements: Innovations in analytical instrumentation are enhancing sensitivity, accuracy, and throughput, enabling faster and more comprehensive testing.

PFAS: A persistent challenge

One of the most pressing issues in environmental testing today is the detection and analysis of PFAS. These synthetic chemicals are widely used in industrial applications and consumer products, including non-stick cookware, waterproof fabrics, and firefighting foams. However, their resistance to degradation has led to significant contamination of water supplies, soil, and even the human body.

PFAS are linked to a range of health concerns, including hormonal disruptions, immune system effects, and an increased risk of certain cancers. Regulatory bodies worldwide are responding by establishing lower thresholds for PFAS detection in drinking water and the environment.

Detecting PFAS poses unique challenges due to their chemical stability and low concentration levels. Advanced techniques such as liquid chromatography-tandem mass spectrometry (LC-MS/MS) have become essential for their accurate identification and quantification. This technology offers the sensitivity and specificity needed to meet regulatory requirements and protect public health.

📚 Download the Analysis of PFAS and Other Environmental Contaminants in Soil and Oat Plants Using High-Resolution GC/MS poster that showcases various methods for extracting and analysing PFAS and other pollutants from soil and oat plants using the GC/Q-TOF system: https://chemetrix.co.za/wp-content/uploads/2024/12/po-7250-pcdl-pfas-asms-2024-tp073-en-agilent.pdf

Emerging Trends in Environmental Testing

Focus on emerging contaminants

Beyond PFAS, other contaminants such as microplastics, pharmaceuticals, and endocrine-disrupting compounds are gaining attention. These pollutants often originate from industrial discharges, agricultural runoff, and consumer waste, making their detection critical for environmental protection.

Analytical techniques like gas chromatography-mass spectrometry (GC-MS) and LC-MS/MS are increasingly used to identify these substances. Their ability to detect compounds at ultra-trace levels is driving innovation in environmental monitoring.

Increased adoption of High-Resolution Mass Spectrometry (HRMS)

High-resolution mass spectrometry is revolutionising environmental analysis by enabling the detection of unknown and emerging contaminants. Its ability to perform non-targeted analysis allows laboratories to identify previously uncharacterised compounds, paving the way for proactive environmental management.

Automation and digitalisation

Laboratories are embracing automation to enhance efficiency and reduce human error. Automated sample preparation systems and robotic workflows streamline processes, allowing labs to handle higher volumes of samples without compromising quality.

Digitalisation also plays a pivotal role, with data analytics and cloud-based platforms enabling real-time monitoring, sharing of results, and improved traceability. These advancements are critical as labs face increasing demands for transparency and accountability.

Focus on sustainability

Environmental testing laboratories are prioritising sustainable practices by minimising waste, reducing energy consumption, and adopting green chemistry techniques. Instrument manufacturers are responding by developing energy-efficient systems and methods that use fewer reagents and solvents.

📚 Download the Automated System for the Routine Cleanup of Environmental Samples Prior to Instrument Analysis poster to discover the automated system for routine clean-up of samples prior to analysis that is used by this organisation: https://chemetrix.co.za/wp-content/uploads/2024/12/Poster_gpc_enviro_A4_0107.pdf

How Chemetrix Supports Environmental Testing

Chemetrix is at the forefront of providing advanced solutions to address the challenges of modern environmental testing. With a comprehensive portfolio of analytical instruments and expertise in environmental analysis, Chemetrix empowers laboratories to stay ahead of emerging trends.

Advanced analytical tools

Chemetrix offers cutting-edge technologies such as LC-MS/MS and ICP-MS, which are essential for detecting trace contaminants like PFAS, heavy metals, and microplastics. These instruments deliver the sensitivity and precision required to meet stringent regulatory standards.

Expert support and training

From instrument installation to ongoing maintenance, Chemetrix provides unparalleled support to ensure laboratories maximise the performance of their equipment. Comprehensive training support helps lab personnel stay updated on the latest methodologies and best practices.

Customised solutions

Recognising that each laboratory has unique needs, Chemetrix works closely with clients to develop tailored workflows. This approach ensures that labs can optimise their operations while meeting the specific demands of their applications.

Commitment to sustainability

Chemetrix is committed to promoting sustainable practices in environmental testing. By offering energy-efficient instruments and supporting the adoption of green chemistry, Chemetrix helps laboratories reduce their environmental footprint while maintaining high standards of analysis.

A Future-focused approach

As environmental challenges continue to evolve, so too must the methods and technologies used to address them. Emerging contaminants like PFAS underscore the need for innovative approaches to environmental testing, while trends such as automation and sustainability highlight the broader shifts shaping the industry.

📚 Watch The PFAS Lab of the Future webinar to discuss how the PFAS Lab of the Future leverages automated sample collection & preparation strategies to reduce labour and drive productivity >

For laboratories, staying ahead of these changes requires a combination of advanced technology, skilled personnel, and strategic partnerships. With Chemetrix as a trusted partner, labs can confidently navigate the complexities of modern environmental testing, ensuring they remain equipped to protect ecosystems and public health.

The Role of Multimode Microplate Readers in Modern Laboratories

In today’s fast-evolving scientific landscape, versatility and efficiency are paramount. Multimode microplate readers are fast becoming a popular and effective choice for modern laboratories, enabling researchers to conduct a wide range of assays with precision and ease. From absorbance to luminescence beyond, these instruments streamline workflows, reduce operational costs, and enhance reproducibility. Available through Chemetrix, advanced multimode microplate readers provide researchers with cutting-edge technology tailored to diverse applications, such as nucleic acid quantification, protein assays, and enzyme kinetics.

Understanding Multimode Microplate Readers

At their core, multimode microplate readers integrate several detection modes into a single device. This capability eliminates the need for multiple instruments, thereby saving space and resources while expanding a laboratory’s functional capacity.

Unlike single-mode readers, which are limited to one detection method, multimode readers can perform absorgance, fluorescence, luminescence, and time-resolved fluorescence measurements, among others. This versatility makes them ideal for high-throughput screening and routine laboratory applications.

Key applications

Nucleic acid quantification

Accurate nucleic acid measurement is critical in molecular biology and genomics research. Multimode readers facilitate DNA and RNA quantification through fluorescence and absorbance assays, ensuring reliable data for downstream applications such as sequencing or PCR.

Protein analysis

Protein quantification and kinetic studies are central to biochemistry and pharmaceutical research. Multimode readers enable assays like the Bradford or BCA assay, utilising absorbance for robust and repeatable results. Additionally, fluorescence-based protein-binding assays provide insights into protein interactions and conformational changes.

Enzyme kinetics

Enzymes are essential to numerous biological processes and industrial applications. Multimode readers are equipped to perform time-resolved fluorescence and luminescence measurements, offering real-time monitoring of enzymatic reactions. These capabilities help researchers study enzyme activity under various conditions and evaluate inhibitors or activators.

Cell viability and toxicity

In drug discovery and toxicology, understanding cell viability is crucial. Multi-mode readers support assays like MTT and ATP assays, providing critical data on cell health and metabolic activity.

📚 Download the Microplate-Based Cell Viability Assays Using Absorbance, Fluorescence, or Luminescence Detection application brief that demonstrates cell viability technologies that use absorbance, fluorescence, or luminescence detection >

Advantages of Multimode Readers

Flexibility and efficiency

By consolidating multiple detection modes into a single platform, multimode readers enhance workflow efficiency. Laboratories can seamlessly switch between applications without reconfiguring equipment, saving time and reducing errors.

Cost-effectiveness

Investing in a single, multi-functional instrument reduces overall costs compared to purchasing and maintaining separate devices for different assays. Additionally, modern instruments come with extended lifespans and robust support services, ensuring long-term value.

Ease of use

Modern systems, like the Agilent BioTek Synergy Multimode Readers offered by Chemetrix, feature intuitive software interfaces, automated calibration, and built-in protocols. These innovations minimise the learning curve, making the instruments accessible to new and experienced users alike.

Trends in Multimode Microplate Reader development

The development of multimode readers continues to evolve in response to laboratory demands:

Miniaturisation and Automation: Instruments are becoming more compact and are integrating seamlessly into automated workflows, reducing hands-on time and increasing throughput.
Enhanced Sensitivity: Advances in optical systems and detection technologies enable the identification of low-abundance analytes with unprecedented accuracy.
Cloud-Based Data Management: Modern readers increasingly offer cloud integration, facilitating remote monitoring and data sharing across teams.

Trust Chemetrix as your partner in advanced laboratory solutions

Chemetrix provides cutting-edge solutions tailored to the needs of modern laboratories. With applications spanning life sciences, environmental testing, and pharmaceutical development, these systems are designed to deliver precise, reproducible results across a broad spectrum of research fields.

By offering industry-leading instruments such as Agilent BioTek Synergy Multimode Readers, Chemetrix empowers researchers with the tools to meet complex challenges. The Agilent BioTek Synergy H1 multimode reader is a configurable multimode microplate reader, with monochromator-based optics for flexibility, filter-based optics for sensitivity, or both. This hybrid technology offers application versatility and excellent performance in a modular platform to expand as your laboratory’s needs change. Its upgradeable, modular design allows for added detection modes, gas control, and dual reagent injectors as your laboratory workflows evolve.

When you need to bring cost-effective, automated spinning-disk confocal microscopy to a lab, the Agilent BioTek Cytation 10 is a bench-size microplate imaging and analysis workhorse. It combines automated confocal and widefield microscopy with conventional multimode microplate reading in a unique, proprietary design. The automated water-immersion objectives capture more light, driving lower exposure times and reducing phototoxic impacts on live cells. It’s an easy-to-use instrument that delivers high quality analysis.

📚 Watch the Moving Cell Migration Research Forward with BioTek webinar to learn how BioTek’s innovative instruments can simplify your workflows and deliver reliable, reproducible results >

Agilent BioTek Cytation C10 Confocal Imaging Reader

Agilent BioTek Synergy H1 Multimode Reader

By partnering with us, laboratories gain access not only to advanced technology but also to comprehensive support services, including training, maintenance, and technical assistance. This ensures that researchers can focus on innovation while relying on robust, reliable equipment.

📚 Download the 3D Cell Culture: A Review of Current Techniques white paper and learn how 3D systems are advancing research in drug development, disease modelling, and tissue engineering >

The versatility and precision of multi-mode microplate readers have made them essential in modern laboratories. From nucleic acid quantification to enzyme kinetics, these instruments offer unparalleled capabilities that streamline workflows and drive innovation. By delivering on our commitment to top-tier laboratory solutions, researchers can confidently tackle emerging challenges and push the boundaries of discovery.

The Importance of Biopharma Analytical Testing

In the world of biopharmaceuticals, precision and safety are non-negotiable. As companies work to develop advanced therapies and biologics, the role of analytical testing becomes ever more critical. Analytical testing serves as the backbone of biopharma development, ensuring that every product released to the market meets stringent regulatory standards while maintaining the highest safety and efficacy levels. Chemetrix supports this vital process by equipping laboratories with state-of-the-art technologies to optimise testing workflows and ensure regulatory compliance.

Why Analytical Testing Matters in Biopharma

Biopharmaceutical products, including monoclonal antibodies, cell and gene therapies, and vaccines, are inherently complex. Unlike traditional small-molecule drugs, these products are often derived from living cells, making them highly sensitive to variations in manufacturing and storage conditions.

Analytical testing ensures the quality, purity, potency, and stability of biopharmaceuticals throughout their lifecycle, from early development to final product release.

Without rigorous testing, even minor inconsistencies in a product can lead to reduced efficacy, compromised safety, or regulatory non-compliance. By employing advanced analytical methods, biopharma companies can identify impurities, confirm molecular structures, and monitor critical quality attributes (CQAs) that are essential for maintaining product integrity.

📚 Download The Journey to Biopharma infographic to discover streamlined automation and cutting-edge analytics >

Key Phases of Analytical Testing

Early development

During the early stages of biopharma development, testing focuses on characterising the biological product and defining CQAs. Techniques such as mass spectrometry, high-performance liquid chromatography (HPLC), and spectroscopy play a central role in these analyses. These tools help determine factors like molecular weight, structural integrity, and glycosylation patterns.

Process development

As manufacturing processes are developed, analytical testing ensures consistency and scalability. Process-related impurities, such as host cell proteins or residual solvents, must be identified and quantified. Additionally, methods like capillary electrophoresis and liquid chromatography-mass spectrometry (LC-MS) are employed to optimise purification steps and ensure process robustness.

Final product release

Before a product reaches the market, it undergoes comprehensive testing to confirm that it meets regulatory specifications. This includes assays for potency, sterility, endotoxin levels, and stability. Modern analytical platforms, such as multi-mode plate readers and automated systems, provide the throughput and accuracy needed for these critical assessments.

Trends in Analytical Testing for Biopharma

Emergence of advanced techniques

The biopharma industry is increasingly adopting technologies like LC-MS and next-generation sequencing (NGS) to enhance analytical capabilities. These methods allow for greater sensitivity and specificity, enabling researchers to detect low-level impurities and subtle molecular changes that could impact product performance.

Adoption of automation and AI

Automation is transforming analytical testing, reducing human error and increasing throughput. AI-driven software is also being integrated into testing workflows, enabling predictive analytics and more efficient data interpretation.

Focus on emerging therapies

The rise of cell and gene therapies has introduced new challenges for analytical testing. These therapies require novel analytical approaches to address their unique complexities, such as the characterisation of viral vectors and the assessment of genome editing outcomes.

Regulatory compliance and data integrity

With stringent guidelines from organisations like the FDA and EMA, ensuring data integrity has become a top priority. Advanced software systems with audit trails and robust data management capabilities are increasingly essential in biopharma testing.

📚 Watch the Accelerating Analysis in the BioPharma Laboratory webinar to discover biopharma workflow innovations that accelerate the characterisation or pathway profiling in protein work & proteomics research using liquid chromatography Mass Spec >

Driving excellence in Analytical Testing

Chemetrix is at the forefront of supporting biopharma companies with advanced analytical solutions. By offering cutting-edge instruments and technologies, we help laboratories address the challenges of testing biologics and other complex products.

We provide access to industry-leading platforms, including HPLC systems, LC-MS, and next-generation spectroscopy tools. These technologies are designed to deliver high sensitivity and precision, ensuring that every aspect of a biopharmaceutical product is rigorously tested.

The new generation Agilent 1260 Infinity III is a robust instrument that delivers the performance, reliability, and robustness you need for the highest confidence in daily HPLC results. With the freedom to mix and match new modules with existing HPLC instrumentation, it’s possible to maximise uptime and minimise disruption while also getting on the fast track to efficiency, optimizing speed and resolution for analysis.

Moreover, Chemetrix offers comprehensive support services, from installation and training to ongoing maintenance and technical assistance. This ensures that labs can maximise the performance of their analytical equipment and stay ahead of industry demands.

📚 Download the Mass Spectrometry of Macromolecules Using Standard Flow LC/MS application note to discover a robust and sensitive LC/MS method using standard LC flow for the analysis of native protein analysis >

The importance of analytical testing in biopharma cannot be overstated. As the industry continues to evolve, the need for advanced testing methods will only grow. By leveraging state-of-the-art technologies and partnering with trusted providers like Chemetrix, biopharma companies can ensure the safety, efficacy, and quality of their products while meeting regulatory expectations. With our commitment to innovation and excellence, Chemetrix stands as a trusted ally for laboratories navigating the complexities of biopharma analytical testing.

The Role of Fluorescence Microscopy in Cell Biology: Innovations and Challenges

Fluorescence microscopy has become an indispensable tool in cell biology, offering researchers unparalleled insights into the inner workings of cells. By leveraging fluorescent molecules to label cellular components, this technology enables scientists to visualise intricate processes in real-time, from protein interactions to dynamic changes in cell architecture. Despite its transformative impact, fluorescence microscopy comes with its own set of challenges, such as balancing image quality with meaningful data acquisition and overcoming technical limitations.

In recent years, advancements in fluorescence microscopy have revolutionised the way scientists approach biological research. These developments are not only enhancing imaging capabilities but also expanding the range of applications for fluorescence microscopy. With cutting-edge tools and expertise, companies like Chemetrix are playing a pivotal role in helping researchers navigate the complexities of this powerful technology.

The significance of Fluorescence Microscopy

At its core, fluorescence microscopy relies on the emission of light from fluorophores to illuminate specific structures or molecules within a cell. This approach has revolutionised cell biology by providing researchers with the ability to study live cells with minimal interference. Applications span numerous fields, including cancer research, neuroscience, and developmental biology. Researchers can now observe molecular interactions, track cell migration, and analyse gene expression with unprecedented detail.

For example, in cancer research, fluorescence microscopy is instrumental in understanding tumour biology, allowing scientists to monitor the behaviour of cancer cells under different conditions.

In neuroscience, this technology facilitates the study of synaptic connections, shedding light on how neurons communicate. Similarly, in developmental biology, fluorescence microscopy provides real-time insights into how cells differentiate and organise to form tissues and organs.

The versatility of fluorescence microscopy is further enhanced when combined with other advanced imaging techniques. For instance, confocal microscopy can be used alongside fluorescence imaging to enhance spatial resolution, enabling researchers to create detailed three-dimensional reconstructions of cellular structures. The ability to overlay fluorescence imaging with techniques like electron microscopy or live-cell imaging adds another layer of complexity, ensuring a comprehensive understanding of biological phenomena.

📚 Download the Supercharge Your Cell Research brochure an in-depth look at cell analysis portfolio of instruments >

Innovations in Fluorescence Microscopy

Recent advancements are transforming the field of fluorescence microscopy, addressing longstanding issues such as poor signal-to-noise ratios, photobleaching, and spatial resolution limitations.

Super-resolution microscopy techniques like STED (stimulated emission depletion) and PALM (photoactivated localisation microscopy) have overcome the diffraction limit of light, enabling imaging at nanometre-scale resolutions.

This has opened new avenues for studying subcellular structures and processes, such as the organisation of protein complexes or the dynamics of intracellular transport.

Another area of innovation lies in the design of advanced fluorophores. These newer molecules exhibit greater photostability, brighter fluorescence, and reduced phototoxicity, ensuring that prolonged imaging sessions yield consistent and reliable results. Fluorophores such as quantum dots and near-infrared dyes are also expanding the toolkit available to researchers, allowing for multiplexed imaging of multiple targets within the same sample.

Technological advancements in optics and computational imaging have also had a profound impact. Adaptive optics systems are now widely used to correct for distortions caused by biological samples, while machine learning algorithms assist in denoising images and extracting meaningful data from complex datasets. These innovations not only improve the quality of imaging but also enhance the efficiency of data analysis, making fluorescence microscopy more accessible and practical for everyday research.

📚 Watch the Maximising Fluorescent Signal Using Variable Bandwidth Monochromators webinar to see how these cutting-edge tools simplify multiplexing and elevate your research >

Challenges in Fluorescence Microscopy

Despite these innovations, researchers face several challenges in fluorescence microscopy that require careful consideration.

One major issue is the trade-off between image quality and biological relevance. While brighter fluorophores and longer exposure times can enhance image clarity, they also increase the risk of phototoxicity, which can damage live cells and distort experimental outcomes.

Striking the right balance between obtaining clear images and preserving cellular integrity remains a delicate task.

Another challenge is the potential for artefacts introduced by fluorescent labelling. Overloading samples with fluorophores can interfere with natural cellular processes, leading to skewed data. Researchers must carefully optimise labelling protocols to ensure that fluorescence signals accurately represent biological phenomena without disrupting the system being studied.

Additionally, fluorescence microscopy generates massive amounts of data, particularly when used for time-lapse imaging or high-throughput studies. Managing and analysing these datasets require sophisticated computational tools and storage solutions. For researchers who lack access to such resources, extracting actionable insights from their experiments can be an overwhelming task.

📚 Download the Monitoring Cell Cycle Progression Using Microscopy application note to explore how cutting-edge solutions make tracking and analysing cell cycle dynamics faster, more efficient, and more reliable >

How Chemetrix supports researchers

Recognising these challenges, Chemetrix goes beyond providing state-of-the-art microscopy equipment. The company positions itself as a trusted knowledge partner, offering researchers the tools, training, and expertise needed to maximise the potential of fluorescence microscopy.

Chemetrix works closely with labs to select the right imaging platforms tailored to their specific research needs. Whether a lab requires high-throughput imaging systems for drug discovery or advanced super-resolution microscopes for cellular studies, Chemetrix ensures that researchers have access to the best technologies available. We are proud to distribute a variety of Agilent’s Biotek and xCELLigence instruments.

Agilent BioTek Lionheart FX Automated Microscope

Equally important is the company’s focus on training and education. Chemetrix provides support to help researchers and technicians develop the skills required to operate advanced imaging systems effectively. By demystifying the complexities of fluorescence microscopy, these training initiatives empower users to overcome technical barriers and achieve reliable results.

Chemetrix also keeps researchers informed about the latest innovations in fluorescence microscopy, bridging the gap between technological advancements and practical applications. From introducing labs to cutting-edge fluorophore designs to offering guidance on data analysis workflows, the company ensures that African laboratories remain at the forefront of global research trends.

📚 Download the Sample Preparation for Fluorescence Microscopy white paper to discover essential tips and considerations for automating the fluorescence microscopy process and achieving consistent results with fixed cells >

Fluorescence microscopy continues to be a cornerstone of cell biology, providing researchers with unparalleled insights into the molecular mechanisms that drive life. Innovations in imaging technology, from super-resolution microscopy to advanced fluorophore design, are expanding the horizons of what can be achieved. However, challenges such as phototoxicity, artefact management, and data analysis underscore the need for expert guidance and robust support systems.

By offering state-of-the-art tools, tailored training, and ongoing expertise, Chemetrix empowers researchers to navigate the complexities of fluorescence microscopy with confidence. Through its commitment to advancing scientific discovery, Chemetrix plays a vital role in enabling breakthroughs that shape our understanding of biology and improve human health.

Lab Automation for Increased Productivity

In today’s fast-paced scientific landscape, laboratories are under growing pressure to deliver faster, more accurate results while grappling with resource constraints. Lab automation is emerging as a transformative solution, offering a path to increased productivity and efficiency across a variety of industries, from healthcare and pharmaceuticals to environmental testing. Chemetrix is at the forefront of this transformation, equipping African laboratories with state-of-the-art automated solutions to meet rising demands.

What Is Lab Automation?

Lab automation refers to the use of advanced technologies to streamline and optimise laboratory processes. This involves replacing or augmenting manual tasks – such as sample preparation, analysis, and data management – with automated systems that work with greater speed, precision, and consistency.

Key components of lab automation include:

Robotic systems for tasks like pipetting and liquid handling.
Software solutions to manage workflows, collect data, and ensure compliance.
Integrated instruments that combine multiple steps into a single, seamless process.

By automating repetitive or labour-intensive tasks, laboratories can redirect human expertise towards higher-value activities, such as data interpretation and problem-solving.

The benefits of Lab Automation

Enhanced productivity

Automation enables laboratories to process significantly larger volumes of samples in less time. For instance, an automated liquid handling system can perform hundreds of pipetting tasks in the time it would take a technician to complete just a fraction manually.

Improved accuracy and consistency

Human error is a significant concern in manual lab work, especially for processes requiring extreme precision. Automated systems minimise variability, ensuring consistent and reproducible results across large datasets.

Cost efficiency

While the initial investment in automation technology can be substantial, the long-term benefits include reduced labour costs, minimised waste, and faster turnaround times, all of which contribute to overall cost savings.

Data management and integration

Automation often comes with software platforms that streamline data acquisition, storage, and analysis. These systems not only ensure regulatory compliance but also provide actionable insights that drive decision-making.

Flexibility and scalability

Modern automation tools are highly adaptable, allowing labs to scale operations as demand increases or shift workflows to accommodate new research priorities.

📚 Watch the Unraveling the Myths of Laboratory Automation video for compact, modular, and flexible solutions that are ideal for both expert and novice users alike >

Applications of Lab Automation

Lab automation is making a significant impact across various domains, offering tailored solutions to meet specific challenges. In clinical diagnostics, automation has revolutionised workflows by enabling high-throughput testing for complex panels, such as infectious diseases or genetic screening. This capability proved invaluable during the COVID-19 pandemic, as diagnostic laboratories were inundated with unprecedented sample volumes. Pharmaceutical research also benefits from automation, particularly in drug discovery processes.

Automated high-throughput screening allows researchers to test thousands of compounds efficiently, expediting the identification of viable drug candidates and accelerating their path to market.

Environmental testing is another area experiencing profound benefits from automation. Laboratories tasked with monitoring water quality or detecting contaminants rely on automated systems for streamlined sampling and analysis. These tools ensure compliance with regulatory standards while maintaining operational efficiency. Similarly, the food safety sector has adopted automation to enhance pathogen detection and allergen testing, ensuring both consumer safety and product quality. By addressing the unique demands of each sector, lab automation is enabling laboratories to deliver reliable, timely results across diverse applications.

Trends Shaping Lab Automation

Emerging trends in lab automation highlight how technology is reshaping traditional workflows to create smarter, more efficient laboratories. One key trend is the integration of artificial intelligence (AI) into automated systems. AI enables advanced data analysis and predictive modelling, helping labs process vast datasets more effectively while identifying subtle patterns that might otherwise go unnoticed. For instance, AI can optimise experimental designs or predict equipment failures, ensuring seamless operations.

Miniaturisation and microfluidics also play a transformative role. Technologies like lab-on-a-chip systems allow laboratories to perform complex assays on a much smaller scale, reducing reagent use and waste while enhancing analytical precision. These compact systems are particularly advantageous for laboratories with limited resources or space.

Additionally, the rise of Internet of Things (IoT) devices has facilitated remote monitoring and control of laboratory equipment. This capability not only boosts productivity but also enhances safety by reducing the need for physical intervention in potentially hazardous environments.

Together, these advancements reflect the dynamic nature of lab automation, equipping laboratories with the tools to tackle future challenges while pushing the boundaries of scientific innovation.

📚 Watch The Answer is Digitisation webinar to learn how automating processes and connecting instruments can drive efficiency and set your lab on the path to innovation >

Bringing automation to African laboratories

Chemetrix is committed to empowering laboratories across Africa with cutting-edge automation solutions. By offering advanced technologies tailored to the unique challenges of the region, we help labs optimise productivity, maintain accuracy, and meet growing demands.

Our portfolio includes a wide range of automated instruments and platforms, from liquid handlers and robotic workstations to integrated systems for high-throughput screening. Beyond providing equipment, Chemetrix offers comprehensive support, including training, maintenance, and software integration, ensuring clients can fully harness the benefits of lab automation.

Lab automation is not just a trend; it is a necessity for modern laboratories aiming to stay competitive in a demanding scientific landscape. By automating key processes, labs can achieve unparalleled levels of productivity, precision, and scalability. With Chemetrix as a partner, laboratories in Africa are well-equipped to embrace the future of science, leveraging innovative technologies to drive progress and deliver impactful results.

📚 Download the Automated Plasma Proteomic Sample Preparation application note to discover a protocol that will make your workflow much more efficient and make the preparation of hundreds or even thousands of plasma samples more feasible >

Improving Lab Efficiency for Business Growth

Lab managers play a pivotal role in ensuring the smooth and efficient operation of laboratories, contributing to the success of research and development activities. It’s a tough job as their responsibilities are diverse and cover various aspects of lab management, from administrative tasks to technical oversight.

Over the years, Agilent has conducted independent global surveys of lab managers from different market segments. The objective of the surveys is to understand lab managers’ pain points and find out what they need to address their most pressing concerns, as well as reveal the differences and similarities of the challenges they face.

Why lab efficiency is important

Lab efficiency is a fundamental aspect of successful lab management, driving productivity, quality, safety, and financial performance. An efficient lab is able to control its time and resources to ensure project milestones and deadlines are met. It’s also important to maintain consistent procedures and protocols, leading to more reliable and accurate results. With an optimised workflow, labs can enjoy quicker completion of tasks and experiments, accelerating the pace of research and development. Finally, by streamlining processes, labs can increase the throughput of experiments and projects without a proportional increase in costs or resources.

Watch our webinar on how to Free Your Workflows From Common Time Traps >

In a nutshell, an efficient lab operates at a higher level of productivity, with greater accuracy, and with ideal use of resources. Sounds simple, right? Well, achieving optimal efficiency in a lab is not so straightforward and Agilent’s surveys have revealed the challenges and pain points lab managers face in getting efficiency right.

What lab managers want

In Agilent’s survey, “‘Understanding Key Challenges and Pain Points in the Global Laboratory Market’, 45% of respondents indicated that they face significant pressure to process more samples. These pressures stem from advancements in technology, rising demand across various sectors, and the need for faster and more accurate results.

The pain point for lab managers is that they have to be able to grow the lab’s business without raising costs. So, it’s quite demanding to tackle more samples but not increase expenses. Where Chemetrix can help is offering incredible analytical technology that is much more flexible, adaptable and able to process more samples with greater accuracy in analysis. As our product portfolio includes variations options, our expert team is able to listen to the needs of lab managers and advise potential solutions that can offer great return on investment. This can help the lab grow and thrive without drastically increasing operating costs.

Improved workflow is another challenge for lab managers, with 75% of global respondents saying that instrument maintenance and downtime are their biggest challenges. In pharma labs specifically, around 90% of respondents said that having reliable and accurate instruments would be the top two factors that would best improve workflow.

For business to grow, business has to flow, and that means the instruments should be humming along without downtime. In many instances, preventative maintenance can help labs avoid unplanned downtime. This is why Chemetrix recommends instruments that provide digital alerts for regular maintenance so that lab staff can take care of the equipment before any challenges arise. In addition to smart technology, Chemetrix also provides great instrument support. From online troubleshooting guides to our Fresh Desk support system, we’re able to help labs quickly so they can continue their valuable work.

Watch the webinar on how to Reduce Instrument Downtime With Usage-Based Maintenance >

Download the brochure on 5 Tips To Prevent Unplanned Lab Downtime >

When people think of business growth for labs, the automatic assumption is that space will grow as well. This may not be the case as smaller labs might not be able to or might not want to move into bigger premises for any number of reasons. 75% of lab managers surveyed in Agilent’s global research indicated they believe space-saving analytical instruments can help overcome the challenge of small lab premises.

It’s true that lab instruments are becoming smaller and much more space-efficient. Certain instruments can do more in a smaller footprint than some larger instruments and possibly fit right in to an existing instrument setup. Chemetrix is able to assess laboratory space requirements and recommend instruments that are robust and powerful but will occupy less bench space. This can improve business efficiency through improved instrument configuration and allowing some more space for other tasks or instruments.

Support efficiency for labs to thrive

Efficient labs ensure consistent quality and reliability, fostering innovation and maintaining a competitive edge. It is crucial for business growth because it leads to increased productivity, cost savings, and faster turnaround times, which enhance customer satisfaction and speed to market. For lab managers, there are additional benefits because it improves employee satisfaction and retention, allowing for focused professional growth. Delving into the process of tackling these challenges and pain points also provides valuable data-driven insights for strategic decision-making, driving long-term business success and adaptability.

What Chemetrix can do is support the goals of lab managers and truly listen to their challenges and pain points to provide effective solutions. We are more than an analytical instrument supplier – we are a partner in the business journey. Our track record and decades-long relationships with laboratories that have grown into successful operations prove that we understand the need for business efficiency and we are more than able to help labs and lab managers achieve their goals.

Unveiling the Hidden Threats: Researching Emerging Contaminants in Water

The water we have on Earth is finite. Although we have water in abundance, caring for this resource has been one of the world’s most pressing environmental challenges. Sadly, we simply do not know the vast majority of chemicals that are discharged into the environment through human activities. For this reason, the detection and identification of these compounds are essential for accurate toxicological profiling of environmental samples.

Ensuring water quality and safety through analytical testing is crucial for public health and environmental protection. Comprehensive testing involves analysing regulated pollutants, including pesticides, semi-volatile organic compounds, metals, and disinfection byproducts. It also extends to emerging contaminants such as PFAS, microplastics, hormones, and various unknown chemicals.

As environmental challenges continue to evolve, detecting and identifying emerging contaminants in water has become a critical task for researchers. Advanced analytical technologies, such as high-resolution mass spectrometry (HRMS), gas chromatography-mass spectrometry (GC-MS), and liquid chromatography-tandem mass spectrometry (LC-MS/MS), play a pivotal role in this effort. These sophisticated instruments not only enhance the detection capabilities but also contribute to a deeper understanding of the toxicological impacts of unknown chemicals.

The role of advanced analytical technologies

High-Resolution Mass Spectrometry (HRMS)

HRMS provides unparalleled precision and accuracy in measuring the mass of chemical compounds. It allows for the detection of a wide range of contaminants, even those present at trace levels. This technology is particularly beneficial for non-targeted analysis, where the goal is to identify unknown compounds in water samples. By delivering high-resolution data, HRMS enables researchers to pinpoint the exact mass of contaminants, facilitating their identification and characterisation.

Watch our webinar on Using Liquid Chromatography with QTOF High-Resolution Mass Spectrometry to Identify Emerging Contaminants in Urban Waters >

Gas Chromatography-Mass Spectrometry (GC-MS)

GC-MS is a powerful tool for separating and analysing volatile and semi-volatile organic compounds. It combines the separation capabilities of gas chromatography with the detection prowess of mass spectrometry. This technology is essential for identifying contaminants that may not be detectable through other means. GC-MS excels in providing detailed information about the chemical composition of water samples, making it indispensable for comprehensive water quality assessments.

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

LC-MS/MS is renowned for its sensitivity and specificity in detecting and quantifying contaminants. This technology is particularly effective for analysing non-volatile and polar compounds that are challenging to detect with GC-MS. LC-MS/MS allows researchers to conduct multi-residue analysis, detecting multiple contaminants simultaneously. Its high throughput and precision make it a cornerstone in environmental monitoring and toxicological studies.

New threats emerging

Microplastics are tiny synthetic particles or polymeric matrices derived from plastic, ranging from 1 µm to 5 mm in size and insoluble in water. According to an article published by Agilent, current research believes that microplastics will also degrade into smaller particles on a nanoscale, called ‘nanoplastics’. Despite increasing analysis, their environmental risk remains unclear. The World Health Organisation (WHO) has called for more scientific research to better understand the potential toxicity of microplastics.

Download the infographic poster on Accurate Microplastics Analysis >

A recent study found that humans could be consuming between 39,000 to 52,000 microplastic particles a year.

A recently published study* stated, “The prevalence of micro and nanoplastics (MNPs) in various environmental and human compartments has highlighted the need for analytical methods to accurately detect and quantify these contaminants. Pyrolysis-gas chromatography coupled with mass spectrometry (Py-GC-MS), one of the thermo-analytical methods, is evolving as an analytical technique to quantify MNPs in complex matrices.”

This study evaluated the impact of using diverse polystyrene (PS) standards with different molecular weights, polydispersity indexes, tacticity, end-capping, and chain branching, on quantifying the mass concentration of PS in various products. The results for the PS-based products showed inconsistencies across different standards, indicating that the measurements for a single product varied substantially when different polystyrene (PS) standards were applied.

The team behind the study made use of Agilent technologies for their research and found there is a need for refined calibration strategies and standardised reference materials to improve the reliability of the MNP analysis method.

From this example, it’s clear that advanced analytical technologies are not only about detection but also about understanding the broader implications of contaminants, like microplastics. By accurately identifying and understanding newer chemicals and contaminants, researchers can assess their toxicological impacts on human health and the environment. This knowledge is crucial for developing effective mitigation strategies and regulatory policies.

Watch our webinar on Microplastics Analysis Just Got Easier: Analysis Direct On-Filter >

Continuous improvement of water analysis

Chemetrix is at the forefront of providing state-of-the-art analytical instruments that empower researchers in their quest to safeguard water quality. By offering cutting-edge technologies such as HRMS, GC-MS, and LC-MS/MS, Chemetrix supports comprehensive environmental research. The instruments are designed to meet the rigorous demands of modern laboratories, ensuring reliable and accurate results.

A prime example of the application of these technologies is non-targeted analysis in water. This approach involves screening water samples for a wide array of contaminants without prior knowledge of their presence. By employing HRMS, GC-MS, and LC-MS/MS, researchers can detect and identify unknown compounds, providing a holistic view of water quality. This method is essential for uncovering emerging contaminants that may not be included in routine monitoring programs.

To preserve our planet’s resources for future generations, the scientific community has to be the trailblazers of today that’ll help find the solutions to protect our tomorrow. There is an incredible amount of passion and dedication among the researchers and scientists who are fighting the good fight against emerging water contaminants and providing valuable insights that everyone can use to make better choices. They can’t do this work without great analytical instruments.

Agilent 8700 LDIR Chemical Imaging System

These instruments enhance detection capabilities, provide valuable insights into toxicological impacts, and support informed decision-making. Chemetrix’s commitment to providing cutting-edge solutions underscores its vital role in environmental research. As we continue to face new environmental challenges, the adoption of these advanced technologies will be crucial in ensuring the safety and sustainability of our water resources.

*Quantitation of polystyrene by pyrolysis-GC-MS: The impact of polymer standards on micro and nano plastic analysis by M. Brits, B. van Poelgeest, W. Nijenhuis, M.J.M. van Velzen, F.M. B´een, G.J.M. Gruter, S.H. Brandsma, M.H. Lamoree