The Agilent TRS100 Raman system is ideal for fast assay of tablets, capsules, and other dosage forms. Transmission Raman technology from Agilent enables simple method-development and deployment in QC applications. It is easy to implement in analytical laboratories and production areas, and has regulatory approvals for content uniformity (CU), assay, and identification (ID) applications. This online seminar provides a comprehensive introduction to the Transmission Raman technology and the Agilent TRS100 Raman system in the pharmaceutical quality-control applications.
Yanqia Wang, PhD, Application Engineer, Molecular Spectroscopy, Agilent Technologies, Inc.
Dr. Yanqia Wang started working for Agilent Technologies Inc. as a FTIR application Engineer in 2013, providing pre-&post-sale application support. The products he covers from Bench-top FTIR microscopes to various Mobile FTIR spectrometers. Dr. Wang received his PhD of analytical chemistry from Duke University in 2004, doing dynamic IR spectroscopy research. Then he joined Fitzpatrick Center for Photonics at Duke University, doing Tissue Raman spectrometer instrumentation. Since 2007, Dr. Wang worked for Avery Dennison Corp. as a spectroscopist, providing molecular analytical support to the research & development.
Drug dissolution testing provides necessary in vitro drug release information for pharmaceutical manufacturing quality control, making it a critical tool for performance characterization of diverse dosage forms. Agilent offers pharmaceutical dissolution testing products for product formulation and other applications.
Merits of Automated Sampling in Dissolution Testing
Dissolution Systems Source Book
Residual solvent impurities in pharmaceuticals are trace amounts of volatile organic compounds used in drug production that remain in the final drug product. Strict regulations require close monitoring on the presence of residual solvent, as even trace amounts can impact drug safety and efficacy.
Satisfy Requirements for Residual Solvent Analysis
Residual Solvents Analysis Using an Agilent Intuvo 9000 GC with 8697 Headspace Sampler
Analysis of USP Method <467>
With increasing awareness of the potential harmful effects of inorganic contaminants, regulatory organizations have provided new guidelines recommending analytical techniques, such as ICP-OES and ICP-MS, to monitor elemental impurities. Agilent offers integrated solution for confident elemental impurities testing.
USP <232>/<233> and ICH Q3D Elemental Impurities Analysis by ICP-OES
USP <232>/<233> and ICH Q3D Elemental Impurities Analysis: Agilent’s ICP-MS solution
Support for 21 CFR Part 11 and Annex 11 Compliance: SDA Module for Agilent ICP-MS MassHunter Software
Simplified QC for Pharmaceutical Elemental Impurity Analysis
Several drug products were recently recalled due to the presence of unacceptable amounts of mutagenic nitrosamine impurities. Chemetrix offers relevant GC/MS, LC/MS and high-throughput MS-based analytical technologies to accurately detect and quantify trace mutagenic and genotoxic impurities in drug products.
Nitrosamine Impurities Application Guide
Determination of Nitrosamine Impurities Using the Ultivo Triple Quadrupole LC/MS
Quantification of Nitrosamine Impurities in Metformin Using Agilent GC/MS/MS Instrumentation
Determine Nitrosamines Using LC/MS in Metformin-Based Drugs
Determination of a Genotoxic NDMA Impurity Using the High-Resolution Agilent 6546 LC/Q-TOF in Ranitidine
Extractables and leachables (E&Ls) analysis is challenging and requires complete confidence in the results to ensure regulatory compliance. No single analytical tool can analyze all E&Ls; we offer diverse analytical technologies and expertise for the accurate identification and quantification of potential E&Ls.
Analysis of Extractable/Leachable Compounds from Generic Liquid Drug Formulations Using GC/MSD Systems
Analysis of Extractable and Leachable (E&L) Compounds Using a Low-Energy EI-Capable High-Resolution Accurate Mass GC/Q-TOF