Standardised ISO Methodologies for the Assessment of Microplastics

As interest in microplastics in the environment and food chain grows, so does the interest in the potential impacts on environmental and human health. This, coupled with strong public attention, has led to various organizations worldwide looking towards the potential for regulations. For example, the European Chemical Agency is currently considering restrictions on the use of microplastics in the form of microbeads in personal care products. Furthermore, the first ISO standard document with general guidelines will be published this year. It can be expected that this will directly impact both official and contract laboratories and producers of drinking water, food, and other relevant products, which will need to better understand the amount, number, size, and ID of microplastic particles in their products. Alongside this broad approach, several countries are developing the standard testing methodology for microplastics in water, and the environment and organizations have been conducting interlaboratory studies as a step towards harmonization of testing methodologies to ensure the comparability of results. 

During this webinar, we will explore the development of these standard methodologies and some of the key challenges faced in their implementation.

 

What will you learn

  • What progress has been made in the development of standardised methodologies for microplastics?
  • What are some of the key challenges that remain in implementing these methodologies?
  • How might these developments impact other areas and the potential for implementing regulations?

 

Who should attend this webinar

  • Microplastics researchers
  • Microplastics analysts from commercial, QA, or research labs who seek to understand how their methods might be compatible with developing standardised methodologies
  • Those interested in the contamination of wastewater, seawater, freshwater, air, sediments, and food (such as fish, shellfish, crustaceans, and bottled water)

 

Dr. Anja Sokolowski
Senior Project Manager
DIN Standards Committee Water Practice

 

Dr. Andreas Kerstan
Product Specialist
Agilent Technologies

 

Register and watch on demand >

 

Vitamins & Amino Acids Analysis for Nutrition Labelling

The vitamins A, C, D, E, B6, B12, folate, and the minerals selenium, zinc, copper, and iron, are essential for normal immune function. Dietary supplements are highly in demand to boost immunity and prevent deficiencies in these nutrients. Dietary supplements and their raw materials are diverse, from an extract in a tablet to a tea packet, milk, or oil bottle in the kitchen. Producers and regulators ensure that active compounds are present in these supplements at the levels expected.

Geographic origin, freshness, and production-type can affect health benefits and also require testing. LC and GC methods focus on known compounds of importance with many outlined by reference bodies like IOC, ISO, FSSAI, and USP. Agilent Technologies is excited to be holding the Food Quality Analysis Program, in collaboration with FSSAI.

Join our webinars to learn about workflow solutions for analysis of nutritional parameters in food, through faster identification and detection at low levels.

 

Ansuman Mahato
Application Specialist LC
Agilent Technologies

 

Register and watch on demand >

 

Become a Better Chromatographer

Whether you are new to practicing GC chromatography, or would like a refresher, the installation and care of your GC column is of the utmost importance.

Join us as we discuss proper column installation and handling for all Agilent GCs including the Intuvo 9000. We will also address the common modes of column degradation and some of the misconceptions that people have concerning column degradation. Lastly, we will discuss ways that you can protect and maintain your column’s lifetime and performance while minimising instrument downtime.

 

Mark Sinnott
Application Engineer
Agilent Technologies, Inc.

 

Mark Sinnott works for Agilent Technologies as a Technical Support Engineer in the Consumables and Supplies Division (CSD) at the capillary column manufacturing facility (the “J&W Scientific” location). In his position at Agilent, Mark performs technical support and applications assistance to gas chromatographers worldwide. He has more than 22 years of experience in gas chromatography, including environmental analysis of compounds in air, soil and water matrices, including dissolved gas analysis for the electrical industry. Mark holds a Master’s Degree in Chemistry from California State University, Sacramento, and currently resides in Sacramento.

 

Ryan Birney
Application Engineer
Agilent Technologies, Inc.

 

In Ryan’s current role at Agilent, he provides application assistance and technical support for GC and Spectroscopy. He has been supporting Agilent in technical and sales roles for the past seven years. Ryan came to Agilent from industry, and has an BS degree in Biochemistry.

 

Register and watch on demand >

 

Analysis of Terpenes in Cannabis Cultivars

This on-demand webinar is a comparison of headspace and SPME-arrow injection techniques for the analysis of terpenes in cannabis cultivars.

Prof. Dr. Götz Schlotterbeck
Dean Study Program Chemistry / Bioanalytics & Cell Biology and Analytical Chemistry FHNW (University of Applied Sciences and Arts), Muttenz, Switzerland

 

Watch on demand >

 

Analytical Strategies for USP Residual Solvents Analysis

In this presentation, we will present the relevant GC/FID and GC/FID/MS based analytical strategies to confidently detect and quantify Class 1, 2, and 3 as well as unknown solvents in drug products. Learn how taking advantage of dual channel configuration and Agilent’s Smart, Connected, and Self-Aware systems can help you successfully meet your requirements for residual solvent analysis and ensure your testing is right first time and every time.

 

What will you learn

  • Understand what residual solvent impurities are and why it’s important to characterise and quantify them, even when present in trace amounts
  • Understand the current regulatory guidelines for residual solvent analysis in drug substance and product
  • Learn about the approaches for the confident identification and quantification of residual solvents

 

Who should attend this webinar

  • Laboratory managers
  • Chromatographers
  • Analytical chemists and scientists
  • New product developers
  • Pharma quality control managers

 

Ian Eisele
Applications Chemist,
Gas Phase Separation Division,
Agilent Technologies

 

Youjuan Zhang
Applications Chemist,
Gas Phase Separation Division,
Agilent Technologies

 

Register and watch on demand >

 

Preventive and Routine Maintenance for Your HPLC System

Similar to our cars needing regular oil changes, tire pressure adjustments, or washer fluid top ups, our HPLC systems also need routine maintenance in order to keep them performing at their best.  Even if you pay a mechanic to change your oil or a Field Service Engineer to change your pump seals, you should still know how frequently these preventive maintenance activities need to occur.

 

This presentation will look at several key issues, such as:

  • How often typical preventive maintenance (PM) tasks should be performed.
  • What signs to look for that may indicate a need for maintenance.
  • Tools for testing the LC systems before and after maintenance.
  • Basic troubleshooting and diagnostics.

The goal of this talk is to lay a strong and broad foundation from which to build a better understanding of your own HPLC systems and their specific maintenance needs.

 

Paul Altiero
Application Engineer
Agilent Technologies, Inc.

 

Paul Altiero is an Applications Engineer located at the Agilent Little Falls site in Wilmington, DE. Prior to coming to Agilent in 2009, Paul worked in the pharmaceutical industry performing LCMS bioanalysis supporting Drug Discovery DMPK. While at Agilent, Paul has been a field service engineer for LCMS as well as the integrating program manager for the RapidFire high throughput LCMS system. In his current role Paul’s responsibilities include technical support and application assistance for LCMS consumables.

 

Register and watch on demand >

 

HPLC Column Care

Are you just getting started with a new column you have never used before? Are you looking for ways to help your columns last a bit longer? These are some of the most common questions asked of our HPLC columns technical support team. In this webinar, we will discuss best practices for HPLC column care, including reversed phase, SEC, HILIC and more. This will include initial equilibration, benchmarking a new column, column storage, and other tips to help make your columns last longer.

 

Mark Powell
Application Engineer
Agilent Technologies, Inc.

 

Mark Powell is an Applications Engineer located at Agilent’s Little Falls site in Wilmington, DE. Before joining Agilent in 2011, Mark worked in the pharmaceutical industry synthesizing, purifying and analyzing drug candidates. He provides applications assistance and technical support for Agilent’s HPLC columns and consumables.

 

Register and watch on demand >

 

Analysis of Nitrosamine Impurities in Pharmaceuticals

What you will learn

  • Understand what mutagenic impurities are and why it’s important to characterize and quantify them, even when present in trace amounts.
  • Understand the current regulatory guidelines for nitrosamines analysis in drug substance and product in Angiotensin II Receptor Blockers (sartan), ranitidine and metformin drugs
  • Learn about approaches for the prevention of the formation of GTIs and the confident identification and quantification of nitrosamines in APIs and drugs

 

Who should attend

  • Laboratory managers
  • Chromatographers
  • Analytical chemists and scientists
  • New product developers
  • Pharma manufacturing and quality control managers

 

Raman V.V.S.S. Nanduri, Ph.D.
Director,
Analys Lab Pvt. Lt

 

Register and watch on demand >

 

Characterisation of Non-Ionic Surfactants

In this talk, we will show characterization of ethoxylation in non – ionic surfactants. In the first dimension the separation is by degree of ethoxylation, while in the second dimension by the separation occurs by the length of the hydrophobic tail. This makes identification and quantitation possible in a single run. Using Agilent 2D LC MassHunter 11 software coupled with the G6230A Accurate Mass Time of flight instrument. We have both quantitative and qualitative data. We can show ppb levels of quantitative detection with Personal Compound Database Library (PCDL) matching in a Walkup environment that a plant QC technician can use.

 

Sue D’Antonio
Applications Scientist
Agilent Technologies, Inc.

 

Sue D’Antonio joined Agilent (HP at that time) more than 30 years ago. For the last 15 years Sue has been an Applications Scientist in the Liquid Phase Separations Group. Sue’s application support extends to HPLC, UHPLC, CE and LCMS across a wide range of markets and customers.

 

Register and watch on demand >

 

Per and Polyfluoroalkyl Substances in Soils

Graphitized carbon black (GCB) has been used widely in sample preparation for efficient removal of pigments and other matrix interferences. However, GCB may cause the loss of some analytes. Carbon S is an advanced hybrid carbon material with optimized carbon content and pore structure. Compared to GCB, Carbon S provides equivalent or better pigment removal from sample matrices, while significantly improving recovery for some GCB-selective analytes (such as planar pesticides). As a result, Carbon S sorbent provides a better balance between analyte recovery and matrix removal efficiency than traditional GCB sorbent. The Carbon S sorbent is applied in the same SPE cartridge format with the same bed mass as GCB SPE. The Carbon S SPE cartridges can be used as a replacement for the GCB cartridges for applications where SPE methodology is used. This study investigates the post-extraction matrix cleanup of 59 PFAS from loamy sand, reed sedge peat, and topsoil using the Bond Elut Carbon S 250 mg, 6 mL cartridges followed by LC/MS/MS analysis.

 

Matt Giardina
Applications Chemist
Agilent Technologies, Inc.

 

Matthew Giardina is an applications chemist at Agilent Technologies focusing on the development of sample preparation techniques for challenging environmental applications. He has been with Agilent for 10 years and working in the field of analytical chemistry for over 20 years. He received and B.S. in chemistry from the University of Maryland at College Park and Ph.D. in analytical chemistry from the Ohio State University.

 

Register and watch on demand >