During this webinar we will describe the newest breakthrough technologies and applications of Raman, Laser based Infrared and UV-Vis Spectroscopy in Pharma.
This will include use of transmission Raman as an alternative to UPHPLC for content uniformity and polymorph studies. Furthermore, use of a next generation IR instrument using a quantum cascade laser will be described for chemical imaging studies including analysis of tablet component distribution, polymorph distribution, salt exchange and stability studies. New breakthrough technologies for ultra-fast and productive parallel temperature based kinetic studies, protein folding, DNA melting and other temperature related UV-Vis measurements will end this overview.
Speaker
Jan Wülfken Product Specialist – Molecular Spectroscopy Agilent Technologies
Dr. Wuelfken has worked for many years as Product Specialist for Agilent Technolgies in many region of the world, supporting Molecular ( Raman FTIR, Fluorescence nad UV-Vis/NIR) Spectroscopy business.
In this webinar we will focus on raw material identification and will give a detailed comparison about the different spectroscopic techniques FTIR, NIR and Raman as well as an a new special Raman way called “SORS” to measure though opaque containers.
Speaker
Jan Wülfken Product Specialist – Molecular Spectroscopy Agilent Technologies
Dr. Wuelfken has worked for many years as Product Specialist for Agilent Technolgies in many region of the world, supporting Molecular ( Raman FTIR, Fluorescence nad UV-Vis/NIR) Spectroscopy business.
This presentation will cover products from Agilent that make GC connections more robust by utilising new technologies that makes connections easier, leak free and more inert for any application.
Topics covered include: Self Tightening Stainless Column Nuts and ferrules, Press Fits, UltiMetal Plus and Stainless Steel Capillary Tubing, Ferrule Pre-swaging installation tool and MS interface installation tool, among others.
Speaker
Mark Sinnott Application Engineer Agilent Technologies, Inc.
Mark Sinnott works for Agilent Technologies as a Technical Support Engineer in the Consumables and Supplies Division (CSD). In his position at Agilent, Mark performs technical support and applications assistance to gas chromatographers worldwide. He has more than 22 years of experience in gas chromatography, including environmental analysis of compounds in air, soil and water matrices, including dissolved gas analysis for the electrical industry. Mark holds a Master’s Degree in Chemistry from California State University, Sacramento, and currently resides in Twin Falls Idaho.
Ensuring the safety and efficacy of biotherapeutics from research to development, and then from manufacturing to quality control is essential to bring a product to market. Large molecules pose unique challenges for biotherapeutic analyses in that they often require running a panel of tests to ensure product efficacy and safety.
Industry efforts have evolved towards comprehensive analytical workflows that enable researchers to monitor critical quality attributes (CQAs) of highly complex and diverse biotherapeutic molecules.
Part 2: A Deeper Dive into Bioseparations
In the second session of this series we will discuss the range of bioseparation approaches used for characterization of CQAs in more detail. This includes solutions available for native (Size Exclusion, Ion Exchange, HIC) and reduced state (RP, HILIC) bioseparations for analysis of mAbs and other biotherapeutics.
Speakers
Donna Potts Biopharma Market Specialist EMEA IDO Agilent Technologies
Donna is a Biopharma Market Specialist for Agilent Technologies; over the last decade she has been responsible for business development for Agilent analytical solutions in the Biopharma market space. Donna has worked extensively with biomolecules during her career, with a strong emphasis on Life Science and Biopharma applications using LC-MS.
After completing Postdoctoral Research at Boston University School of Medicine, she worked as an application specialist before becoming a Market Specialist in 2013. Donna holds a PhD in Analytical Chemistry from The University of Manchester, UK, where her studies focused on protein quantitation using mass spectrometry.
With more than 20 years of professional experience, Cecilia is presently the Product Specialist for columns and supplies at Agilent. Supporting distributors and laboratory users in the analysis and purification of small and large molecules, for a wide range of LC and GC applications as well as sample preparation.
Cecilia holds a Ph.D. in Chemical Engineering from Rensselaer Polytechnic Institute in US.
Ensuring the safety and efficacy of biotherapeutics from research to development, and then from manufacturing to quality control is essential to bring a product to market. Large molecules pose unique challenges for biotherapeutic analyses in that they often require running a panel of tests to ensure product efficacy and safety.
Industry efforts have evolved towards comprehensive analytical workflows that enable researchers to monitor critical quality attributes (CQAs) of highly complex and diverse biotherapeutic molecules.
Part 1: Introduction to Workflows
This presentation will provide an insight into the basics of the biopharma industry and introduce how analytical tools can be utilised as part of comprehensive workflows for characterisation of CQAs.
Speakers
Donna Potts Biopharma Market Specialist EMEA IDO Agilent Technologies
Donna is a Biopharma Market Specialist for Agilent Technologies; over the last decade she has been responsible for business development for Agilent analytical solutions in the Biopharma market space. Donna has worked extensively with biomolecules during her career, with a strong emphasis on Life Science and Biopharma applications using LC-MS.
After completing Postdoctoral Research at Boston University School of Medicine, she worked as an application specialist before becoming a Market Specialist in 2013. Donna holds a PhD in Analytical Chemistry from The University of Manchester, UK, where her studies focused on protein quantitation using mass spectrometry.
With more than 20 years of professional experience, Cecilia is presently the Product Specialist for columns and supplies at Agilent. Supporting distributors and laboratory users in the analysis and purification of small and large molecules, for a wide range of LC and GC applications as well as sample preparation.
Cecilia holds a Ph.D. in Chemical Engineering from Rensselaer Polytechnic Institute in US.
In the first half of this webinar, we will introduce the ICH/USP regulation and how to measure elemental impurities with the Agilent ICP-OES and/or ICP-MS instruments.
The second part of the webinar will focus on the Agilent software compliance solutions where you will see our options for data integrity as well as software features that simplify validating methods according to ICH/USP.
Speakers
Uwe Noetzel EMEAI Technical Coverage and Solutions Agilent Technologies
Uwe joined Agilent as a GC/LC MS specialist in 1989. Since 1994 he is involved in ICP-MS as a Product Specialist. In 2001 he became part of the Agilent International Distributor Organization (IDO). Today his responsibility is the full Agilent Atomic Spectroscopy Portfolio in IDO
Andrew Brotherhood
Atomic Spectroscopy Application Engineer
Agilent Technologies
Andrew has over 15 years’ hands-on experience with ICP-MS, ICP-OES and Ion Chromatography instrumentation. He has mainly worked in the pharmaceutical analysis industry gaining significant experience with developing and validating methods to pharma regulations. Andrew started working for Agilent as a full time employee in January 2018 working as an Atomic Spectroscopy Application Engineer based at the Agilent Centre of Excellence in the UK.
As interest in microplastics in the environment and food chain grows, so does the interest in the potential impacts on environmental and human health. This, coupled with strong public attention, has led to various organizations worldwide looking towards the potential for regulations. For example, the European Chemical Agency is currently considering restrictions on the use of microplastics in the form of microbeads in personal care products. Furthermore, the first ISO standard document with general guidelines will be published this year. It can be expected that this will directly impact both official and contract laboratories and producers of drinking water, food, and other relevant products, which will need to better understand the amount, number, size, and ID of microplastic particles in their products. Alongside this broad approach, several countries are developing the standard testing methodology for microplastics in water, and the environment and organizations have been conducting interlaboratory studies as a step towards harmonization of testing methodologies to ensure the comparability of results.
During this webinar, we will explore the development of these standard methodologies and some of the key challenges faced in their implementation.
What will you learn
What progress has been made in the development of standardised methodologies for microplastics?
What are some of the key challenges that remain in implementing these methodologies?
How might these developments impact other areas and the potential for implementing regulations?
Who should attend this webinar
Microplastics researchers
Microplastics analysts from commercial, QA, or research labs who seek to understand how their methods might be compatible with developing standardised methodologies
Those interested in the contamination of wastewater, seawater, freshwater, air, sediments, and food (such as fish, shellfish, crustaceans, and bottled water)
Speaker
Dr. Anja Sokolowski Senior Project Manager
DIN Standards Committee Water Practice
Dr. Andreas Kerstan
Product Specialist
Agilent Technologies
The vitamins A, C, D, E, B6, B12, folate, and the minerals selenium, zinc, copper, and iron, are essential for normal immune function. Dietary supplements are highly in demand to boost immunity and prevent deficiencies in these nutrients. Dietary supplements and their raw materials are diverse, from an extract in a tablet to a tea packet, milk, or oil bottle in the kitchen. Producers and regulators ensure that active compounds are present in these supplements at the levels expected.
Geographic origin, freshness, and production-type can affect health benefits and also require testing. LC and GC methods focus on known compounds of importance with many outlined by reference bodies like IOC, ISO, FSSAI, and USP. Agilent Technologies is excited to be holding the Food Quality Analysis Program, in collaboration with FSSAI.
Join our webinars to learn about workflow solutions for analysis of nutritional parameters in food, through faster identification and detection at low levels.
Whether you are new to practicing GC chromatography, or would like a refresher, the installation and care of your GC column is of the utmost importance.
Join us as we discuss proper column installation and handling for all Agilent GCs including the Intuvo 9000. We will also address the common modes of column degradation and some of the misconceptions that people have concerning column degradation. Lastly, we will discuss ways that you can protect and maintain your column’s lifetime and performance while minimising instrument downtime.
Speaker
Mark Sinnott Application Engineer Agilent Technologies, Inc.
Mark Sinnott works for Agilent Technologies as a Technical Support Engineer in the Consumables and Supplies Division (CSD) at the capillary column manufacturing facility (the “J&W Scientific” location). In his position at Agilent, Mark performs technical support and applications assistance to gas chromatographers worldwide. He has more than 22 years of experience in gas chromatography, including environmental analysis of compounds in air, soil and water matrices, including dissolved gas analysis for the electrical industry. Mark holds a Master’s Degree in Chemistry from California State University, Sacramento, and currently resides in Sacramento.
Ryan Birney
Application Engineer Agilent Technologies, Inc.
In Ryan’s current role at Agilent, he provides application assistance and technical support for GC and Spectroscopy. He has been supporting Agilent in technical and sales roles for the past seven years. Ryan came to Agilent from industry, and has an BS degree in Biochemistry.
Every single food item we purchase in a store has a label or two. While we can sometimes overlook the labels, they are doing a vital job. Food labelling helps to promote consumer confidence and trust in the food industry by providing them with the information they need to make informed decisions about the foods they eat. It also helps to promote transparency, safety, and fair trade practices in the food industry.
But what does it all really mean for consumers, how does it affect consumers and why should consumers be aware of the laws relating to food labelling? It is because there is expectation and trust on the part of the consumer. The consumer expects a supplier of foodstuffs to comply with the relevant laws relating to their product and trust that the manner in which the foodstuff is handled, and the information that is presented to the consumer regarding a product, is true and not misleading. From allergen declarations, the amount of sugar present in a product right down to the storage instructions of a foodstuff, consumers are fast becoming more conscious of what is in their foodstuffs.
Food labelling in South Africa
In South Africa, food labelling is regulated by the Department of Health through the Foodstuffs, Cosmetics and Disinfectants Act (Act 54 of 1972) and the Regulations Relating to the Labelling and Advertising of Foodstuffs (R146). The regulations also require that labels be written in English, but may also include one or more of the other official languages of South Africa, such as Afrikaans, isiZulu, or Sesotho.
All food products sold in South Africa must have labels that include certain mandatory information such as the product name, ingredients list, net quantity, country of origin, and the name and address of the manufacturer or importer. Common allergens must be declared on a label and the manner in which allergens must be declared is regulated by R146.
Date marking is a piece of mandatory information on a label. It must be indicated on the label and in the following manner: “best before”, “BB” and/or “use by” and/or “sell by”. Any person is prohibited from removing or altering the date marking. However, it is important to note that when the “best before” dates have been reached, it does not mean that the food is unsafe, but that it may be past its best. “Use by” is somewhat more instructive and often applies to refrigerated items where the risk of microbiological spoilage can be expected to increase after a given date. “Sell by” is a store guideline to ensure that goods still have a reasonable shelf life after sale.
If there are claims made on a label, such as “High in fibre” it is mandatory to have a nutritional table on the label. If the nutritional table has been indicated on the label, whether voluntarily by the manufacturer or due to the fact that a claim has been made on the label, the Regulations relating to the Foodstuffs Act (R146) prescribes a very specific format in which the nutritional information must be presented. Amongst other requirements, the nutritional information must be presented in the tabular format, energy content must be declared in “kilojoules” or “kJ”, and the amount of each nutrient present in the foodstuff must be expressed per 100 g/ml and per single serving.
South Africa has also done some pioneering things in terms of food manufacturing and food labelling. South Africa was the first country in the world to require mandatory fortification of staple foods with vitamins and minerals, including wheat flour, maize meal, and rice. The fortification of these foods is aimed at addressing the country’s high levels of nutrient deficiencies. In 2018, South Africa also implemented a new regulation requiring the warning label “high in sugar” on food and drinks with more than 17.5 grams of sugar per 100 millilitres. This regulation is aimed at addressing the country’s high rates of obesity and related health problems.
Importance for suppliers
Labelling legislation in South Africa is complex and must be looked at as a whole and not each part in isolation. In addition to the multitude of legislations pertaining to food labelling, there is also no single regulatory authority on labelling of foodstuffs. Bearing all this in mind, and although it can be a bit overwhelming, consumers must be aware of their rights and where to go should they have a complaint.
Suppliers and retailers must also take note of the many food labelling legislations which will impact their marketing, designing of labels and ultimately their relationship with the consumer. With new labelling Regulations in the pipeline gearing to replace R146, understanding the complex nature of our South African labelling legislation has never been more important.
(This article contains information originally published by the Food Advisory Consumer Services)
