Water Analysis | Pesticides

Pesticides & Herbicides compounds used to control weeds, mold, bacteria, insects, and rodents are widely used throughout the world. Due to their widespread use, agricultural chemicals find their way into the food chain, water supply, and soil resulting in potentially dangerous exposure levels to humans. While not fully understood, exposure to pesticides may interfere with neurological development and disrupt a person’s endocrine system. For a complete characterization and sensitive quantification of pesticides in the environment, both an LC-MS and GC-MS system are required. Agilent’s complete workflow solutions for pesticides analysis include sample preparation products, chromatography, mass spectrometry, data reporting and expert application services, provide everything needed to tackle challenges associated with pesticide analysis in the environment.

 

Resources

Measurement of Underivatized Glyphosate and Other Polar Pesticides in Surface and Drinking Water

Application Note

Analysis of Drinking Water with the Agilent 8860 GC and 7697A Headspace Sampler

Application Note

Analysis of Parathion-Ethyl in Water with 85 μm Polyacrylate SPME Fibers

Application Note

Water Analysis | Disinfection Byproducts

Disinfection byproducts (DBPs) are formed when organic matter in water reacts with disinfectants used to kill microbes at water treatment plants. DBPs consist of a large variety of mainly halogenated compounds that have been shown to have adverse health effects on humans. Reseach shows that that they may be carcinogenic and may cause both developmental and reproductive issues in humans and wildlife. Common DBP classes are trihalomethanes (THMs), haloacetic acids (HAAs) and Nitrosamines, a class of DBPs that have been shown to be carcinogenic at extremely low ng/L levels. Agilent triple quadrupole LC- & GC-MS systems are the ideal instruments for low-level detection (sub-parts per trillion) of emerging & unregulated DBPS in drinking water.

To identify new disinfection byproducts, the Agilent Q/TOF instruments are ideal partners, offering high-resolution accurate mass analysis with simple yet powerful software tools.

 

Resources

Nitrosamines Analysis in Drinking Water Using GC/MS/MS—Meeting Equivalence to EPA Method 521

Application Note

Finding NDMA Precursors Using Accurate Mass Tools with an Agilent 6540 Q-TOF LC/MS

Application Note

Determination of Haloacetic Acids in Water by GC/μECD Using Agilent J&W DB-35ms Ultra Inert and DB-XLB Columns

Application Note

Water Analysis | Volatile and Semi Volatile Organics

Large groups of Volatile organic compounds (VOCs) & Semi-Volatile organic compounds (sVOCs) have been found to be harmful to the environment as well as toxic to humans and are monitored in both drinking water and wastewater supplies by environmental regulators. Due to their diversity and widespread use, VOCs & sVOCs can occur from a variety of products such as paints and hydraulic fluids to dry-cleaning products and refridgerants as well as petroleum based products and gasoline. VOCs comprise a large and disparate list of compounds that include more common compounds such as aldehydes, ketones, halogenated compounds as well as several other potentially harmful compounds.sVOCs comprises of a broad number of priority pollutants such as polycyclic aromatic hydrocarbons (PAHs), polychlorinated biphenyls (PCBs), nitro-aromatics . Many are considered potentially carcinogenic, mutagenic, and disruptive to human health.

Accurate, reliable and efficient trace-level analyses of VOCs & sVOCs are required. Regulatory agencies set the threshold limits based on threat, toxicity, and target matrix. While contaminants are often analyzed via GC or GC/MS, it can be difficult to guard against potentially costly and dangerous false positives. To meet this challenge, Agilent developed the Inert Flow Path for GC analysis.

Agilent’s 7697A Headspace Sampler, when coupled with the market leading 8890 GC and 5977B Mass Spectrometer, delivers accurate and reliable analysis of VOCs & sVOCs in water. Purge & Trap techniques, that are supported by Agilent, is another way to analyze regulated VOCs in water using GC-MS.

 

Resources

Determination of Benzene and its Derivatives in Water with the Agilent 8697 Headspace Sampler and 8890 GC

Application Note

Improved volatiles analysis using static headspace, the 5977B GC/MSD and a high-efficiency source

Application Note

US EPA Method 8260 with the Tekmar Atomx XYZ P&T and the Agilent 7890B GC/5977A MS

Application Note

Analysis of Analysis of Semivolatile Organic Compounds in Drinking Water on the Agilent Intuvo and 5977 With Extended Calibration Range

Application Brief

Aromatic Hydrocarbons Analysis in Environmental Samples

Brochure

Software

Chemetrix laboratory software offers the control that businesses demand, as well as the flexibility and technical functionality that cutting-edge labs require. Our portfolio includes data systems for analytical instrument control and data analysis, Lab Information Management (LIMS) and Inventory Management Systems and additional software packages for data visualization and mining.

 

Chromatography Data Systems

OpenLab Software portfolio is an integrated suite of products that includes sample management, data acquisition, data analysis, data management, lab workflow management. These products easily integrate to work together to cover the analytical workflow from the moment the analytical request is generated until the data are archived. OpenLab software improves lab throughput and the quality of your results and will be an integral part of your data integrity strategy.

 

Tutorials

OpenLab CDS for ChemStation Users Submitting and Managing Runs


OpenLab CDS for ChemStation Users Acquisition Methods


OpenLab CDS for ChemStation Users – Control Panel

OpenLab CDS for ChemStation Users – Create a Sequence

OpenLAB Chemstation – Editing an Existing Intelligent Report

OpenLAB Chemstation – How to Create a Multi-level Calibration Curve

OpenLAB CDS – How to Zoom In and Out of a Chromatogram


OpenLAB CDS – How to view Audit Trails

 

Resources

Data Integrity Tips for Laboratories Part 1

Download PDF

 


MassHunter

The MassHunter software suite supports efficient data acquisition, qualitative data analysis, quantitative data analysis, and reporting for Agilent GC/MS, LC/MS and ICP-MS systems.

 

Tutorials

How to summate peaks in MassHunter Quant

The use of Sublists in MassHunter Quant

MassHunter PDF Report Builder Existing Templates and Column Edits

Cell Analysis

With over 20,000 genes, 200,000 proteins and thousands of pathways, you can’t measure everything in a cell at once, but you can measure the energy that drives them. Chemetrix offers cell analysis technology solutions that detect discrete changes in cellular bioenergetics in real-time. Real-time cell measurements provide a clear window into the critical functions driving cell signaling, proliferation, activation, toxicity and biosynthesis. Move beyond analysing what your cells are, and reveal a clearer measure of what they do.

 

Best Practices & Fundamentals

Procedures, Techniques and Resources for a Successful Xf Assay.

 

Training

Energy Pathways Video

Seahorse XF Training Webinar – Gather Assay Materials

Fundamentals | Measuring Cell Metabolism – Transient Micro-chamber

ICP Chromatography Mass Spectrometry

Chemetrix’s market-leading inductively coupled plasma mass spectrometry (ICP-MS) systems provide flexible and reliable solutions for elemental analysis. Our single quadrupole ICP-MS and triple quadrupole (ICP-QQQ) instruments offer the highest matrix tolerance and unmatched interference removal, delivering fast, accurate, and consistently reproducible results, even for trace metals.

 

Concepts & Fundamentals

Learn about ICP-MS principles, concepts and their main components, as well as best practices, Tips & Tricks.

 

Fundamentals

The principles of ICP-MS

Principles

This is How you ICP-MS: Mastering the Art of Cone Performance

Executive Overview

 

Tips & Tricks

A collection of useful guides.

Guidelines for Trouble Shooting and Maintenance of ICP-MS Systems

Presentation

Agilent ICP-MS Interactive Troubleshooting tool for Low sensitivity

Presentation

The secret way to double-check an ICP-MS result without rerunning the sample

How to do an ICP-MS analysis from outside the lab

How to dilute ICPMS samples without using liquid diluent

Using Helium mode to deal with tricky chemistry in ICP-MS analysis

Liquid Chromatography Mass Spectrometry

Chemetrix liquid chromatography/mass spectrometry (LC/MS) brings powerful analytical capability to a wide range of applications. Complete LC/MS workflows feature sample preparation, InfinityLab chromatography, and Agilent mass spectrometry, as well as software to acquire high-quality data and turn it into definitive answers. The Chemetrix LC/MS family provides the capabilities and performance to solve virtually any analytical challenge.

 

Concepts & Fundamentals


Learn about LC-MS principles, concepts and their main components, as well as best practices, Tips & Tricks.

 

Fundamentals

Discover the Fundamentals of Mass Spectrometry.

Fundamentals of Mass Spectrometry Theory

Presentation

Basics of LC/MS

Primer

 

LC-MS Concepts

Concept guides to our Triple Quad and High-Resolution QTOF instruments

Agilent 6400 Series Triple Quadrupole LC/MS

Concepts Guide

Agilent 6200 Series TOF and 6500 Series Q-TOF LC/MS System

Concepts Guide

Dissolution

Chemetrix offers a robust and innovative portfolio of pharmaceutical dissolution testing products. Our systems are designed to meet regulatory guidelines and integrate the latest technologies for product formulation and other applications. Our dissolution product range expanded through the acquisitions of the VanKel Technology Group and Varian Scientific Instruments.

 

Best Practices & Fundamentals

Learn about dissolution testing systems and their main components, as well as best practices, Tips & Tricks

 

Tips & Tricks

Useful Tips for the Agilent 708-DS System & Autosamtes Sampling Station

Agilent Tips and Tricks 708-DS Dissolution Apparatus

Fundamentals Webinar Series

A three-part series that covers the fundamentals of Dissolution.

1. Fundamentals of Dissolution

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2. Dissolution Best Practices and Qualification

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3. Agilent’s Advanced Dissolution Systems & Software

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