(PFAS) are persistent, bioaccumulative, and a health concern, calls for more regulatory guidance and stringent requirements have increased. As a market leader in environmental analysis for over 40 years, Agilent offers complete start-to-finish workflows for extraction, screening, quantification, and reporting of PFAS in water and environmental samples.
Persistent organic pollutants (POPs) include many different and diverse classes of chemicals including dioxins, furans, polychlorinated biphenyls (PCBs), polybrominated diethyl ethers (PBDEs), polyaromatic hydrocarbons (PAHs), endrin, DDT and others. Research shows that POPs are extremely toxic to humans and wildlife even at very low concentrations. Pharmaceuticals and personal care products (PPCPs) & hormones enter our water supplies through human excretion, domestic and industrial disposal into wastewater treatment plants, agricultural runoff and animal feed lot operations. One of the negatives effects that active hormones found on excrement can have on both humans and wildlife is endocrine disruption, which may occur at extremely low ng/L levels. PPCPs are quite resilient and are difficult to remove through conventional water treatment processes, resulting in persistence in the environment and potential accumulation over time. Agilent offers complete solutions including online and offline solid phase extraction techniques, and LC-MS and GC-MS systems to analyze PPCPs, hormones and POPs at required sensitivity and accuracy levels in the environment.
Contamination in our waterways, soil, air, and drinking water from microplastics is gaining significant public interest due largely to its emergence as an environmental threat.
Researchers are now working towards standardized analytical solutions to best characterize
these small particles in terms of chemical identity, size, shape, and total mass.
Ensuring the quality of drinking water is a primary goal for public health around the world. Most countries have enacted regulations and monitoring programs to ensure that the supply of drinking water is free from potentially harmful chemicals. The regulations typically include maximum allowable concentrations for a range of inorganic components. Trace metals are routinely monitored in both the treated water supplied to households, and the source water used for drinking water abstraction (from rivers, reservoirs, lakes, underground aquifers; and, in some regions, seawater used for desalination).
Pesticides & Herbicides compounds used to control weeds, mold, bacteria, insects, and rodents are widely used throughout the world. Due to their widespread use, agricultural chemicals find their way into the food chain, water supply, and soil resulting in potentially dangerous exposure levels to humans. While not fully understood, exposure to pesticides may interfere with neurological development and disrupt a person’s endocrine system. For a complete characterization and sensitive quantification of pesticides in the environment, both an LC-MS and GC-MS system are required. Agilent’s complete workflow solutions for pesticides analysis include sample preparation products, chromatography, mass spectrometry, data reporting and expert application services, provide everything needed to tackle challenges associated with pesticide analysis in the environment.
Disinfection byproducts (DBPs) are formed when organic matter in water reacts with disinfectants used to kill microbes at water treatment plants. DBPs consist of a large variety of mainly halogenated compounds that have been shown to have adverse health effects on humans. Reseach shows that that they may be carcinogenic and may cause both developmental and reproductive issues in humans and wildlife. Common DBP classes are trihalomethanes (THMs), haloacetic acids (HAAs) and Nitrosamines, a class of DBPs that have been shown to be carcinogenic at extremely low ng/L levels. Agilent triple quadrupole LC- & GC-MS systems are the ideal instruments for low-level detection (sub-parts per trillion) of emerging & unregulated DBPS in drinking water.
To identify new disinfection byproducts, the Agilent Q/TOF instruments are ideal partners, offering high-resolution accurate mass analysis with simple yet powerful software tools.
Large groups of Volatile organic compounds (VOCs) & Semi-Volatile organic compounds (sVOCs) have been found to be harmful to the environment as well as toxic to humans and are monitored in both drinking water and wastewater supplies by environmental regulators. Due to their diversity and widespread use, VOCs & sVOCs can occur from a variety of products such as paints and hydraulic fluids to dry-cleaning products and refridgerants as well as petroleum based products and gasoline. VOCs comprise a large and disparate list of compounds that include more common compounds such as aldehydes, ketones, halogenated compounds as well as several other potentially harmful compounds.sVOCs comprises of a broad number of priority pollutants such as polycyclic aromatic hydrocarbons (PAHs), polychlorinated biphenyls (PCBs), nitro-aromatics . Many are considered potentially carcinogenic, mutagenic, and disruptive to human health.
Accurate, reliable and efficient trace-level analyses of VOCs & sVOCs are required. Regulatory agencies set the threshold limits based on threat, toxicity, and target matrix. While contaminants are often analyzed via GC or GC/MS, it can be difficult to guard against potentially costly and dangerous false positives. To meet this challenge, Agilent developed the Inert Flow Path for GC analysis.
Agilent’s 7697A Headspace Sampler, when coupled with the market leading 8890 GC and 5977B Mass Spectrometer, delivers accurate and reliable analysis of VOCs & sVOCs in water. Purge & Trap techniques, that are supported by Agilent, is another way to analyze regulated VOCs in water using GC-MS.
Chemetrix laboratory software offers the control that businesses demand, as well as the flexibility and technical functionality that cutting-edge labs require. Our portfolio includes data systems for analytical instrument control and data analysis, Lab Information Management (LIMS) and Inventory Management Systems and additional software packages for data visualization and mining.
OpenLab Software portfolio is an integrated suite of products that includes sample management, data acquisition, data analysis, data management, lab workflow management. These products easily integrate to work together to cover the analytical workflow from the moment the analytical request is generated until the data are archived. OpenLab software improves lab throughput and the quality of your results and will be an integral part of your data integrity strategy.
The MassHunter software suite supports efficient data acquisition, qualitative data analysis, quantitative data analysis, and reporting for Agilent GC/MS, LC/MS and ICP-MS systems.
With over 20,000 genes, 200,000 proteins and thousands of pathways, you can’t measure everything in a cell at once, but you can measure the energy that drives them. Chemetrix offers cell analysis technology solutions that detect discrete changes in cellular bioenergetics in real-time. Real-time cell measurements provide a clear window into the critical functions driving cell signaling, proliferation, activation, toxicity and biosynthesis. Move beyond analysing what your cells are, and reveal a clearer measure of what they do.
Procedures, Techniques and Resources for a Successful Xf Assay.
Chemetrix’s market-leading inductively coupled plasma mass spectrometry (ICP-MS) systems provide flexible and reliable solutions for elemental analysis. Our single quadrupole ICP-MS and triple quadrupole (ICP-QQQ) instruments offer the highest matrix tolerance and unmatched interference removal, delivering fast, accurate, and consistently reproducible results, even for trace metals.
Learn about ICP-MS principles, concepts and their main components, as well as best practices, Tips & Tricks.
The principles of ICP-MS
A collection of useful guides.
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