Specification: xC RT | RTCA

The Agilent xCELLigence RTCA eSight enables comprehensive insight into cell health, cell behavior, cell function and cell biology processes using live, simultaneous, and real time biosensor impedance-based and image-based measurements. The eSight system combines the label-free xCELLigence RTCA technology with live cell imaging in 3 colors (red, green, and blue). This combination allows for informative live cell analysis and increased insight into cell health. 

The Agilent xCELLigence RTCA ePacer provides an easy and effective way to produce functionally mature hiPSC cardiomyocytes. The ePacer improves the maturation status of the cardiomyocytes in 2-3 weeks using precise and electrical pacing conditions over different time durations. The simple pacing protocol, using precise and consistent electrical pacing conditions, improves the functionality of hiPSC cardiomyocytes and their response to inotropic compounds.

The Agilent xCELLigence RTCA S16 instrument uses biosensors to continuously monitor live cell proliferation, morphology change, and attachment quality in a label-free and real-time manner. The instrument operates in a standard CO₂ cell culture incubator and the control unit is housed outside the incubator. User friendly software allows for real-time control and monitoring of the instrument with real-time data analysis functions.

The Agilent xCELLigence RTCA Cardio instrument monitors cardiomyocyte activity for cardiotoxicity assessment. The contraction-relaxation cycle of cardiomyocytes gives rise to a distinct, rhythmic fluctuation in impedance that is readily captured on the millisecond time scale. Changes in the intensity and periodicity in impedance are monitored in seconds or in days to assess cardiomyocyte contractility and viability in the presence of various drugs. The Agilent xCELLigence RTCA Cardio instrument analyzes cells in an electronic 96-well plate format (E-Plate Cardio 96), which are placed in a standard CO₂ cell culture incubator and interface via a cable with analysis and control units that are housed outside the incubator.

The Agilent xCELLigence Real-Time Cell Analysis (RTCA) SP instrument uses label-free cellular impedance to continuously monitor cell health, behavior, and function with high accuracy, sensitivity, and reproducibility. The SP model can run a 96-well electronic microplate. The instrument operates in a standard CO2 cell culture incubator and the control unit is housed outside the incubator. Simply plate cells and begin monitoring cell behavior to obtain real-time kinetic data for assay windows that stretch from seconds to days. Online data acquisition and offline data analysis are easy to perform using RTCA Software Pro.

The Agilent xCELLigence RTCA DP instrument continuously measures cell invasion and migration(CIM) and monitors cell health, behavior, and function using label-free cellular impedance.

The three cradles on the DP instrument enable three separate electronic 16-well plates to be controlled and monitored in parallel or independently of one another. This flexible plate batch processing allows maximum productivity for multiple users. The instrument operates in a standard CO2 cell culture incubator and the control unit is housed outside the incubator. Online data acquisition and offline data analysis are easy to perform using RTCA Software Pro.

The Agilent xCELLigence RTCA MP instrument uses label-free cellular impedance to continuously monitor cell health, behavior, and function with high accuracy, sensitivity, and reproducibility. The MP model can host up to six 96-well electronic microplates (E-Plate 96), which can be run in parallel or independently of one another. Simply plate cells and begin monitoring cell behavior to obtain real-time kinetic data for assay windows that stretch from seconds to days.Online data acquisition and offline data analysis are easy to perform using RTCA Software Pro.