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    Agilent xCELLigence RTCA Multiple Plate (MP) Instrument 

    The Agilent xCELLigence RTCA MP instrument uses label-free cellular impedance to continuously monitor cell health, behavior, and function with high accuracy, sensitivity, and reproducibility. The MP model can host up to six 96-well electronic microplates (E-Plate 96), which can be run in parallel or independently of one another. Simply plate cells and begin monitoring cell behavior to obtain real-time kinetic data for assay windows that stretch from seconds to days.Online data acquisition and offline data analysis are easy to perform using RTCA Software Pro.

    Features

    • xCELLigence RTCA MP model can run up to six 96-well plates simultaneously or independently, with flexible plate batch processing to maximize productivity for multiple users.
    • MP system measures cell health, viability, or response to treatments with high sensitivity, accuracy, and reproducibility.
    • RTCA MP analyzer obtains continuous data at high temporal resolution (from seconds to days), with non-invasive and label-free real-time impedance technology.
    • Easy workflow allows users to simply add cells to E-plates and begin kinetic measurements at physiological conditions, with minimal hands-on time.
    • Intuitive RTCA Software Pro allows for analysis of real-time data to generate diverse plot types and automatically calculate parameters such as % of cytolysis, IC50 or KT50.
    • The instrument operates in a standard CO2 cell culture incubator and the control unit is housed outside the incubator.

    Applications

    • Cell health characterization
    • Immune cell-mediated killing
    • Viral cytopathic effects
    • Cytotoxicity, cell adhesion
    • Cell barrier function (e.g. TEER)
    • Cell signalling (e.g. GPCR)

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