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    Agilent xCELLigence RTCA Single Plate (SP) Instrument 

    The Agilent xCELLigence Real-Time Cell Analysis (RTCA) SP instrument uses label-free cellular impedance to continuously monitor cell health, behavior, and function with high accuracy, sensitivity, and reproducibility. The SP model can run a 96-well electronic microplate. The instrument operates in a standard CO2 cell culture incubator and the control unit is housed outside the incubator. Simply plate cells and begin monitoring cell behavior to obtain real-time kinetic data for assay windows that stretch from seconds to days. Online data acquisition and offline data analysis are easy to perform using RTCA Software Pro.

    Features

    • Agilent xCELLigence RTCA SP model can run one 96-well plate.
    • Measure cell health, viability, or response to treatments with high sensitivity, accuracy, and reproducibility.
    • Obtain continuous data at high temporal resolution (from seconds to days), with non-invasive and label-free real-time impedance technology.
    • Easy workflow allows users to simply add cells to E-plates and begin kinetic measurements at physiological conditions, with minimal hands-on time.
    • Intuitive RTCA Software Pro allows for analysis of real-time data to generate diverse plot types and automatically calculate parameters such as % of cytolysis, IC50 or KT50.
    • RTCA Software Pro supports FDA 21 CFR Part 11 compliance to ensure electronic data integrity.

    Applications

    • Cell health characterization
    • Immune cell-mediated killing assays
    • Viral cytopathic effects assays
    • Cytotoxicity assays
    • Cell adhesion assays
    • Cell barrier function assays(e.g. TEER)
    • Cell signaling assays (e.g. GPCR)

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