Agilent BIO-DIS Reciprocating Cylinder Apparatus

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Agilent BIO-DIS Reciprocating Cylinder Apparatus

For extended release-rate testing that meets requirements (Apparatus 3) the BIO-DIS is designed to meet current USP Apparatus 3 and EP Reciprocating Cylinder specifications.

Features

Biorelevant—simulate gastrointestinal conditions with simple programming that allows in vitro dissolution pH profiling with biorelevant agitation rates and retention times.
Flexible—useful for release-rate testing of floating dosage forms, beads and chewables. Use one instrument to test and transport a variety of samples, saving valuable bench space. Samples are automatically transported from one medium to the next without operator intervention.
Compliant—be confident knowing the BIO-DIS is compliant with the reciprocating cylinder apparatus, USP Apparatus 3, and EP harmonized specifications.
Easily configured—select a standard volumetric reciprocating cylinder option or small and large volume configuration to meet testing needs for low dose or poorly soluble formulations. Other options include a double row instrument for increased testing throughput (the number of media changes is reduced in half with this option).
Automated sampling—easily perform automated sampling by integrating the Agilent 850-DS dissolution sampling station.
Reporting—the built-in report center printer provides hard-copy documentation of testing progress and conditions. A four-line digital display provides updated operation information as the test progresses.
Software control—available through the 21 CFR compliant dissolution workstation software, which allows direct programming of the BIO-DIS and 850-DS dissolution sampling station along with various pumps and filter changer.
Temperature control—maintain temperature with the standard heater/circulator. All parameters are controlled by the BIO-DIS and entered from the front panel keypad.

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Agilent BIO-DIS Reciprocating Cylinder Apparatus

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