The mystery of the rising “Blanks”

If you’ve ever sat in front of your workstation wondering why your Blank and Background Equivalent Concentration (BEC) values are stubbornly high, you aren’t alone. It is a common frustration for geochemical analysts: your instrument is calibrated, your reagents are fresh, yet the background noise refuses to quieten down. These elevated values aren’t just technical nuisances; they directly impair your Limit of Quantification (LOQ). In a world where a $0.1\text{ g/t}$ difference in a gold tailings project can determine financial success, “noisy” data is a risk you cannot afford to take.

Understanding the noise: BEC and LOQ

To solve the problem, we first have to understand it. The BEC represents the total background signal of your analytical system – essentially the “noise” the instrument sees when no sample is present. When this noise is high, your instrument struggles to distinguish a genuine analyte signal from the background. This directly pushes up your LOQ, making it impossible to accurately quantify the lower concentrations that modern mining exploration demands. The root cause of these high values? It usually comes down to one single, persistent word: CONTAMINATION.

Clean up your act with expert training and standards

If your sample preparation isn’t meticulous, even the most advanced mass spectrometer will produce compromised results. Contamination is a silent thief that enters your workflow through water purity, reagent quality, and even the laboratory personnel themselves – common culprits include cosmetics, jewellery, and the powder in traditional gloves.

The Chemetrix Edge: We don’t just supply tools; we build expertise. Through the Chemetrix Lab Advisor, we provide your team with the specialised skills needed to identify and eliminate these “time traps”. By pairing this training with high-purity Inorganic Ventures Certified Reference Materials (CRMs), you ensure your calibration is built on a foundation of absolute purity.

Practical advice:

• Stop the “Double-dip”: Never pipette directly from the stock bottle; transfer your working volumes into clean, secondary containers like pre-rinsed LDPE bottles.
• Go gravimetric: Switch to weight-based (gravimetric) preparation. Mass doesn’t change with temperature, whereas volume does, leading to more reproducible and auditable results.

Technology that does the heavy lifting

While a clean bench is vital, the right hardware can act as your final line of defence against complex mineral matrices. Mining ores are notorious for their high levels of dissolved solids, which traditionally require extensive manual dilution – a process that introduces even more opportunities for human error and contamination.

The Chemetrix Edge: We recommend the Agilent 7850 / 7900 / 8900 ICP-MS series as the physical solution to these high-matrix challenges. These instruments are equipped with Ultra High Matrix Introduction (UHMI) technology, which uses clean Argon gas to “dilute” your sample aerosol before it even reaches the plasma.

Practical advice:

By using the Agilent 7850’s UHMI system, your lab can directly analyse samples containing up to $25\%$ total dissolved solids without manual liquid dilution. This not only saves hours of labour but practically eliminates the risk of dilution errors and reagent-born contamination.

From waste to wealth: The reward of precision

The ultimate goal of refining your workflow is simple: lower LOQs and higher confidence. When you master your contamination control, you unlock the ability to see value where others see waste. Successful tailings reclamation depends on this precision. By accurately monitoring recovery at trace levels, mining operations can turn legacy liabilities into profitable resources, contributing to a more sustainable and circular mining economy.

Take the next step towards cleaner data

Ready to lower your detection limits and boost your lab’s productivity? It starts with a partnership that understands your specific challenges.

Review your prep: Identify one source of potential contamination today (check those gloves!)

Audit your standards: Ensure your CRMs are matrix-matched to your ores for better accuracy.

Connect with Chemetrix: Let our team of scientists help you tailor a solution that combines Agilent’s world-class technology with practical, on-the-ground support.

Let’s advance science together. Contact Chemetrix today to explore how we can elevate your laboratory’s performance.

]]> https://chemetrix.co.za/from-dust-to-diamonds-how-to-master-trace-metal-analysis-in-modern-mining/feed/ 0 https://chemetrix.co.za/improving-lab-efficiency-for-business-growth/ https://chemetrix.co.za/improving-lab-efficiency-for-business-growth/#respond Wed, 02 Oct 2024 08:00:17 +0000 https://chemetrix.co.za/?p=6654 Continue reading "Improving Lab Efficiency for Business Growth"]]> Lab managers play a pivotal role in ensuring the smooth and efficient operation of laboratories, contributing to the success of research and development activities. It’s a tough job as their responsibilities are diverse and cover various aspects of lab management, from administrative tasks to technical oversight.

Over the years, Agilent has conducted independent global surveys of lab managers from different market segments. The objective of the surveys is to understand lab managers’ pain points and find out what they need to address their most pressing concerns, as well as reveal the differences and similarities of the challenges they face.

Why lab efficiency is important

Lab efficiency is a fundamental aspect of successful lab management, driving productivity, quality, safety, and financial performance. An efficient lab is able to control its time and resources to ensure project milestones and deadlines are met. It’s also important to maintain consistent procedures and protocols, leading to more reliable and accurate results. With an optimised workflow, labs can enjoy quicker completion of tasks and experiments, accelerating the pace of research and development. Finally, by streamlining processes, labs can increase the throughput of experiments and projects without a proportional increase in costs or resources.

Watch our webinar on how to Free Your Workflows From Common Time Traps >

In a nutshell, an efficient lab operates at a higher level of productivity, with greater accuracy, and with ideal use of resources. Sounds simple, right? Well, achieving optimal efficiency in a lab is not so straightforward and Agilent’s surveys have revealed the challenges and pain points lab managers face in getting efficiency right.

What lab managers want

In Agilent’s survey, “‘Understanding Key Challenges and Pain Points in the Global Laboratory Market’, 45% of respondents indicated that they face significant pressure to process more samples. These pressures stem from advancements in technology, rising demand across various sectors, and the need for faster and more accurate results.

The pain point for lab managers is that they have to be able to grow the lab’s business without raising costs. So, it’s quite demanding to tackle more samples but not increase expenses. Where Chemetrix can help is offering incredible analytical technology that is much more flexible, adaptable and able to process more samples with greater accuracy in analysis. As our product portfolio includes variations options, our expert team is able to listen to the needs of lab managers and advise potential solutions that can offer great return on investment. This can help the lab grow and thrive without drastically increasing operating costs.

Improved workflow is another challenge for lab managers, with 75% of global respondents saying that instrument maintenance and downtime are their biggest challenges. In pharma labs specifically, around 90% of respondents said that having reliable and accurate instruments would be the top two factors that would best improve workflow.

For business to grow, business has to flow, and that means the instruments should be humming along without downtime. In many instances, preventative maintenance can help labs avoid unplanned downtime. This is why Chemetrix recommends instruments that provide digital alerts for regular maintenance so that lab staff can take care of the equipment before any challenges arise. In addition to smart technology, Chemetrix also provides great instrument support. From online troubleshooting guides to our Fresh Desk support system, we’re able to help labs quickly so they can continue their valuable work.

Watch the webinar on how to Reduce Instrument Downtime With Usage-Based Maintenance >

Download the brochure on 5 Tips To Prevent Unplanned Lab Downtime >

When people think of business growth for labs, the automatic assumption is that space will grow as well. This may not be the case as smaller labs might not be able to or might not want to move into bigger premises for any number of reasons. 75% of lab managers surveyed in Agilent’s global research indicated they believe space-saving analytical instruments can help overcome the challenge of small lab premises.

It’s true that lab instruments are becoming smaller and much more space-efficient. Certain instruments can do more in a smaller footprint than some larger instruments and possibly fit right in to an existing instrument setup. Chemetrix is able to assess laboratory space requirements and recommend instruments that are robust and powerful but will occupy less bench space. This can improve business efficiency through improved instrument configuration and allowing some more space for other tasks or instruments.

Support efficiency for labs to thrive

Efficient labs ensure consistent quality and reliability, fostering innovation and maintaining a competitive edge. It is crucial for business growth because it leads to increased productivity, cost savings, and faster turnaround times, which enhance customer satisfaction and speed to market. For lab managers, there are additional benefits because it improves employee satisfaction and retention, allowing for focused professional growth. Delving into the process of tackling these challenges and pain points also provides valuable data-driven insights for strategic decision-making, driving long-term business success and adaptability.

What Chemetrix can do is support the goals of lab managers and truly listen to their challenges and pain points to provide effective solutions. We are more than an analytical instrument supplier – we are a partner in the business journey. Our track record and decades-long relationships with laboratories that have grown into successful operations prove that we understand the need for business efficiency and we are more than able to help labs and lab managers achieve their goals.